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. 2017 Feb 2:7:41747.
doi: 10.1038/srep41747.

Short-term monocular occlusion produces changes in ocular dominance by a reciprocal modulation of interocular inhibition

Eva Chadnova  1 , Alexandre Reynaud  1 , Simon Clavagnier  1 , Robert F Hess  1
Affiliations

Short-term monocular occlusion produces changes in ocular dominance by a reciprocal modulation of interocular inhibition

Eva Chadnova et al. Sci Rep. .

Erratum in

Abstract

Ocular dominance can be modulated by short-term monocular deprivation. This changes the contribution that each eye makes to binocular vision, an example of adult cortical neuroplasticity. Optical imaging in primates and psychophysics in humans suggest these neuroplastic changes occur in V1. Here we use brain imaging (MEG) in normal adults to better understand the nature of these neuroplastic changes. The results suggest that short-term monocular deprivation, whether it be by an opaque or translucent patch, modulates dichoptic inhibitory interactions in a reciprocal fashion; the unpatched eye is inhibited, the patched eye is released from inhibition. These observations locate the neuroplastic changes to a level of visual processing where there are interocular inhibitory interactions prior to binocular combination and help to explain why both binocular rivalry and fusional tasks reveal them.

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Conflict of interest statement

The authors declare no competing financial interests.

Figures

Figure 1
Figure 1. Procedures.
(a) The time line showing three baseline measurements, a 2.5 hr period of monocular deprivation using either a black patch or a translucent patch followed by 4 measurements are various times after removal of the patch. (b) The stimulus and its dichoptic presentation using polarized glasses and its temporal frequency tagging. (c) The response frequency spectrum and the temporal frequency tagged components representing the responses of each eye.
Figure 2
Figure 2. Effects of monocular deprivation.
MEG power data for dominant (blue-patched eye) and non-dominant (red- unpatched eye) eyes before and after 150 min of monocular occlusion with either a black patch (top row) or a translucent patch (bottom row). Results are normalized to the pre-patching baseline (unity) and displayed for four time points after removal of the patch. Left column: monocular responses. Middle column: dichoptic responses. Right column: deprivation index.
See this image and copyright information in PMC

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