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. 2017 Mar 1;22(2):e214-e218.
doi: 10.4317/medoral.21422.

Sclerotherapy for the recurrent granulomatous epulis with pingyangmycin

Y Cai  1 , R Sun, K-F He, Y-F Zhao, J-H Zhao
Affiliations

Sclerotherapy for the recurrent granulomatous epulis with pingyangmycin

Y Cai et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Background: Relapse of granulomatous epulis is common after surgery because of local irritations, hormonal level in vivo, or incomplete resection. Currently, if recurrence occurs, then extraction of the teeth adjacent to the lesion is commonly performed, which may influence the aesthetics or masticatory function. Thus, a more effective and less aggressive treatment method is urgently demanded, particularly for the recurring lesion. This study investigated the effects of the intralesional pingyangmycin (PYM) injections for the recurrent granulomatous epulis and assessed the complications.

Material and methods: A total of 16 patients with recurrent granulomatous epulis underwent intralesional PYM injections, between July 2010 and June 2014. The effects and complications of the treatment were retrospectively reviewed.

Results: The total number of injections performed was 48 (for all patients). The median number of injections per patient was three (range, two to four). All cases completely recovered with no recurrence and resorption of the alveolar bone after a follow-up of more than 12 months. The complications included slight bleeding, local swelling and pain following injection. All these symptoms resolved 7 to 10 days after the injection.

Conclusions: In summary, intralesional PYM injections may be a preferred option for recurring granulomatous epulis.

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Conflict of interest statement

Conflict of interest statement:The authors have nothing to disclose.

Figures

Figure 1
Figure 1
The microscopic examination (40×) of the specimens shows the chronic inflammatory granulation tissue with increased vascularity.
Figure 2
Figure 2
A) A bright red, easily haemorrhage and well-defined tumor at the gingiva of the right lower second premolar was relapsed after surgery. (B) The lesion was disappeared after four times intralesional injection of PYM.
Figure 3
Figure 3
The ulceration was found on the surface of the lesion about three days after injection.
See this image and copyright information in PMC

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