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Review
. 2016 Dec;53(12):559-595.
doi: 10.1067/j.cpsurg.2016.11.003. Epub 2016 Nov 29.

Trends and controversies in multidisciplinary care of the patient with breast cancer

Laura S Dominici  1 , Monica Morrow  2 , Elizabeth Mittendorf  3 , Jennifer Bellon  4 , Tari A King  5
Affiliations
Review

Trends and controversies in multidisciplinary care of the patient with breast cancer

Laura S Dominici et al. Curr Probl Surg. 2016 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

I have no conflicts of interest to declare, and the findings presented here have not been published elsewhere.

Figures

Figure 1
Figure 1
Alliance for Clinical Trials in Oncology A11202 trial schema (160). The Alliance A11202 study is a randomized phase III trial that is evaluating the role of ALND in patients with T1–T3 N1 MO breast cancer who have SLN-positive disease after NACT. Specifically, XRT (to the breast or chest wall and nodes) plus ALND is being compared with XRT only in this patient population. ALND, axillary lymph node dissection; BCS, breast-conserving surgery; NACT, neoadjuvant chemotherapy; SLN, sentinel lymph node; XRT, radiotherapy Modified from (114) with permission.
Figure 2
Figure 2
NSABP B-51/RTOG 1304 (NRG 9353) trial schema (161). NRG 9353 is an ongoing randomized phase III clinical trial that is evaluating the role of XRT in patients with documented positive axillary nodes (T1–T3 N1 MO breast cancer) who convert to pathologically node-negative disease after NACT. Specifically, the trial is designed to determine whether patients who undergo BCS can be treated with adjuvant breast XRT alone or require additional nodal XRT, and whether chest-wall and axillary XRT improves outcomes post-mastectomy (versus no XRT). BCS, breast-conserving surgery; ER, estrogen receptor; FNA, fine-need aspirate; NACT, neoadjuvant chemotherapy; NSABP, National Surgical Adjuvant Breast and Bowel Project; pCR, pathological complete response; RTOG, Radiation Therapy Oncology Group; SLNB, sentinel lymph node biopsy; XRT, radiotherapy. Modified from (114) with permission.
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