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Comment
. 2016 Mar 16:1:8.
doi: 10.21037/tgh.2016.01.07. eCollection 2016.

Glypican-1 exosomes: do they initiate a new era for early pancreatic cancer diagnosis?

Laura Lorenzon  1 , Giovanni Blandino  2
Affiliations
Comment

Glypican-1 exosomes: do they initiate a new era for early pancreatic cancer diagnosis?

Laura Lorenzon et al. Transl Gastroenterol Hepatol. .
No abstract available

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Highlights of Melo and associates research (2). (A) Glypican-1 (GPC1) exosomes are detected in human pancreatic cancer and in a pre-malignant lesions (PanIN) mouse model; (B) GPC1 exosomes harbor K-ras mutations; (C) AUC curves for diagnosis reach nearly perfection; (D) corelation between GPC1 exosomes and overall survival (OS) and disease free survival (DFS).
See this image and copyright information in PMC

Comment on

  • Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.
    Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Melo SA, et al. Nature. 2015 Jul 9;523(7559):177-82. doi: 10.1038/nature14581. Epub 2015 Jun 24. Nature. 2015. PMID: 26106858 Free PMC article.

References

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