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Review
. 2017 Mar;46(1):61-76.
doi: 10.1016/j.gtc.2016.09.010.

Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea

Michael A Silverman  1 , Liza Konnikova  2 , Jeffrey S Gerber  3
Affiliations
Review

Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea

Michael A Silverman et al. Gastroenterol Clin North Am. 2017 Mar.

Abstract

Antibiotic treatment alters the composition and metabolic function of the intestinal microbiota. These alterations may contribute to the pathogenesis of necrotizing enterocolitis (NEC) and antibiotic-associated diarrhea (AAD). Recent studies are beginning to unravel the contribution of specific groups of microbes and their metabolic pathways to these diseases. Probiotics or other microbiota-targeted therapies may provide effect strategies to prevent and treat NEC and AAD.

Keywords: Antibiotic-associated diarrhea; Antibiotics; Clostridium difficile; Microbiome; Necrotizing enterocolitis; Probiotics.

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Figure 1
Figure 1
Timeline of microbiome development in premature and term infants
See this image and copyright information in PMC

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