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Comment
. 2017 Feb 6:6:e24896.
doi: 10.7554/eLife.24896.

The eyes have it

Mehmet Keleş  1 , Mark A Frye  1
Affiliations
Comment

The eyes have it

Mehmet Keleş et al. Elife. .

Abstract

Molecular genetic experiments are revealing how the fly brain generates behavioral responses to visual stimuli.

Keywords: D. melanogaster; feature detection; lobula; loom detection and avoidance behaviors; neuroscience; optic glomeruli; retinotopy; visual behavior.

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Conflict of interest statement

The authors declare that no competing interests exist.

Figures

Figure 1.
Figure 1.. Transforming visual signals into motor actions.
(A) Visual features that are important to the fly include looming (top), small moving objects, colors, and vertical edges. (B) Wu et al. identified 22 different classes of visual projection neurons (VPNs) in the lobula (Lo), with all the neurons in a given class projecting to a specific glomerulus in the brain. Five examples are shown schematically. Wu et al. also observed that the neurons have dendritic innervations within anatomically distinct layers of the lobula (indicated by white dashed lines). (C) Neighboring columns of neurons in the lobula (indicated by black dashed lines) sample neighboring regions of space. The neurons in a given VPN class have overlapping dendritic fields, which corresponds to overlaps in the sampling of visual space. The axon terminals, on the other hand, completely innervate the glomerulus for that VPN class. (D) It is thought that each VPN class responds to a visual feature (panel A) and contributes to a particular form of behavior (panel D).
See this image and copyright information in PMC

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References

    1. Borst A. Fly visual course control: behaviour, algorithms and circuits. Nature Reviews Neuroscience. 2014;15:590–599. doi: 10.1038/nrn3799. - DOI - PubMed
    1. Card G, Dickinson MH. Visually mediated motor planning in the escape response of Drosophila. Current Biology. 2008;18:1300–1307. doi: 10.1016/j.cub.2008.07.094. - DOI - PubMed
    1. Keleş M, Frye M. Object-detecting neurons in Drosophila. Current Biology. 2017 doi: 10.1016/j.cub.2017.01.012. - DOI - PMC - PubMed
    1. Mu L, Ito K, Bacon JP, Strausfeld NJ. Optic glomeruli and their inputs in Drosophila share an organizational ground pattern with the antennal lobes. Journal of Neuroscience. 2012;32:6061–6071. doi: 10.1523/JNEUROSCI.0221-12.2012. - DOI - PMC - PubMed
    1. Strausfeld NJ. Atlas of an Insect Brain. Berlin: Springer-Verlag; 1976.

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