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Review
. 2017 Feb 4;18(2):330.
doi: 10.3390/ijms18020330.

The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host

Qi Hui Sam  1 , Matthew Wook Chang  2   3 , Louis Yi Ann Chai  4   5
Affiliations
Review

The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host

Qi Hui Sam et al. Int J Mol Sci. .

Abstract

The advent of sequencing technology has endowed us with the capacity to study microbes constituting the human commensal community that were previously non-culturable. Much of the initial works have concentrated on the bacterial flora constituting the gut microbiome, since specimens are readily accessible in health and disease. Less, however, is understood of the "silent population"-the fungal species, also known as the mycobiome. Living in symbiosis with bacteria as commensals in our body, it is perceivable that the mycobiome exerts an inadvertent influence on the microbiome. We review here the recent knowledge gained from study of the interaction between the mycobiome and microbiome in health and disease susceptibility, immunity, and consequences from antimicrobial treatment.

Keywords: fungus; gastrointestinal; gut microbiome; microflora; mycobiome; pathobiont.

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Conflict of interest statement

The authors declare no conflict of interest. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, and in the decision to publish the results.

Figures

Figure 1
Figure 1
The multifaceted factors influencing gut microbiome and mycobiome interaction.
See this image and copyright information in PMC

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