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Comment
. 2017 Jun;83(6):1353-1356.
doi: 10.1111/bcp.13249. Epub 2017 Feb 20.

Response to: 'Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'

Thomas Vanhove  1   2 , Pieter Annaert  3 , Dirk R J Kuypers  1   2
Affiliations
Comment

Response to: 'Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'

Thomas Vanhove et al. Br J Clin Pharmacol. 2017 Jun.
No abstract available

Keywords: 4β-hydroxycholesterol; CYP3A; bodyweight; kidney transplantation; tacrolimus.

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Figures

Figure 1
Figure 1
Correlations between nonbodyweight‐corrected tacrolimus (Tac) apparent oral clearance (Cl/F) and 4β‐hydroxycholesterol/cholesterol (4β‐OHC/C) (A), weight‐corrected Tac Cl/F/W and 4β‐OHC/C/W (B), Tac Cl/F and midazolam (MDZ) Cl/F (C) as well as between bodyweight and Tac Cl/F (D), 4β‐OHC/C (E) and MDZ Cl/F (F)
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References

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