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Comment
. 2017 Feb 6;40(3):215-216.
doi: 10.1016/j.devcel.2017.01.008.

A Tale of Division and Polarization in the Mammalian Embryo

Shankar Srinivas  1 , Tristan Argeo Rodriguez  2
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A Tale of Division and Polarization in the Mammalian Embryo

Shankar Srinivas et al. Dev Cell. .
Free article

Abstract

The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development.

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