Review

. 2017 Mar;34(3):40.

doi: 10.1007/s12032-017-0898-1. Epub 2017 Feb 7.

Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

Affiliations

¹ Department of Oncology, Radiation Oncology, University of Turin, Via Genova 3, 10126, Turin, Italy. pierfrancesco.franco@unito.it.
² Department of Oncology, Radiation Oncology, University of Turin, Via Genova 3, 10126, Turin, Italy.
³ Department of Surgical Sciences, General Surgery 2U and Liver Transplantation Center, University of Turin, Turin, Italy.
⁴ Department of Oncology, Medical Oncology 1, AOU Citta' della Salute e della Scienza, Turin, Italy.
⁵ Department of Oncology, Medical Oncology 1, University of Turin, Turin, Italy.
⁶ Department of Oncology, Medical Oncology 2, AOU Citta' della Salute e della Scienza, Turin, Italy.
⁷ Department of Surgical Sciences, General Surgery 1U, University of Turin, Turin, Italy.

PMID: 28176241
DOI: 10.1007/s12032-017-0898-1

Review

Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

Pierfrancesco Franco et al. Med Oncol. 2017 Mar.

. 2017 Mar;34(3):40.

doi: 10.1007/s12032-017-0898-1. Epub 2017 Feb 7.

Affiliations

¹ Department of Oncology, Radiation Oncology, University of Turin, Via Genova 3, 10126, Turin, Italy. pierfrancesco.franco@unito.it.
² Department of Oncology, Radiation Oncology, University of Turin, Via Genova 3, 10126, Turin, Italy.
³ Department of Surgical Sciences, General Surgery 2U and Liver Transplantation Center, University of Turin, Turin, Italy.
⁴ Department of Oncology, Medical Oncology 1, AOU Citta' della Salute e della Scienza, Turin, Italy.
⁵ Department of Oncology, Medical Oncology 1, University of Turin, Turin, Italy.
⁶ Department of Oncology, Medical Oncology 2, AOU Citta' della Salute e della Scienza, Turin, Italy.
⁷ Department of Surgical Sciences, General Surgery 1U, University of Turin, Turin, Italy.

PMID: 28176241
DOI: 10.1007/s12032-017-0898-1

Abstract

Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein summarize the evidence derived from randomized phase III trials on pre-operative treatments in this oncological scenario.

Keywords: Adenocarcinoma; Gastro-oesophageal junction; Neoadjuvant chemotherapy; Oesophageal cancer; Pre-operative chemo-radiation; Radiotherapy.

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Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

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Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

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