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Meta-Analysis
. 2017 Feb 8;2(2):CD000081.
doi: 10.1002/14651858.CD000081.pub3.

Selective versus routine use of episiotomy for vaginal birth

Affiliations
Meta-Analysis

Selective versus routine use of episiotomy for vaginal birth

Hong Jiang et al. Cochrane Database Syst Rev. .

Abstract

Background: Some clinicians believe that routine episiotomy, a surgical cut of the vagina and perineum, will prevent serious tears during childbirth. On the other hand, an episiotomy guarantees perineal trauma and sutures.

Objectives: To assess the effects on mother and baby of a policy of selective episiotomy ('only if needed') compared with a policy of routine episiotomy ('part of routine management') for vaginal births.

Search methods: We searched Cochrane Pregnancy and Childbirth's Trials Register (14 September 2016) and reference lists of retrieved studies.

Selection criteria: Randomised controlled trials (RCTs) comparing selective versus routine use of episiotomy, irrespective of parity, setting or surgical type of episiotomy. We included trials where either unassisted or assisted vaginal births were intended. Quasi-RCTs, trials using a cross-over design or those published in abstract form only were not eligible for inclusion in this review.

Data collection and analysis: Two authors independently screened studies, extracted data, and assessed risk of bias. A third author mediated where there was no clear consensus. We observed good practice for data analysis and interpretation where trialists were review authors. We used fixed-effect models unless heterogeneity precluded this, expressed results as risk ratios (RR) and 95% confidence intervals (CI), and assessed the certainty of the evidence using GRADE.

Main results: This updated review includes 12 studies (6177 women), 11 in women in labour for whom a vaginal birth was intended, and one in women where an assisted birth was anticipated. Two were trials each with more than 1000 women (Argentina and the UK), and the rest were smaller (from Canada, Germany, Spain, Ireland, Malaysia, Pakistan, Columbia and Saudi Arabia). Eight trials included primiparous women only, and four trials were in both primiparous and multiparous women. For risk of bias, allocation was adequately concealed and reported in nine trials; sequence generation random and adequately reported in three trials; blinding of outcomes adequate and reported in one trial, blinding of participants and personnel reported in one trial.For women where an unassisted vaginal birth was anticipated, a policy of selective episiotomy may result in 30% fewer women experiencing severe perineal/vaginal trauma (RR 0.70, 95% CI 0.52 to 0.94; 5375 women; eight RCTs; low-certainty evidence). We do not know if there is a difference for blood loss at delivery (an average of 27 mL less with selective episiotomy, 95% CI from 75 mL less to 20 mL more; two trials, 336 women, very low-certainty evidence). Both selective and routine episiotomy have little or no effect on infants with Apgar score less than seven at five minutes (four trials, no events; 3908 women, moderate-certainty evidence); and there may be little or no difference in perineal infection (RR 0.90, 95% CI 0.45 to 1.82, three trials, 1467 participants, low-certainty evidence).For pain, we do not know if selective episiotomy compared with routine results in fewer women with moderate or severe perineal pain (measured on a visual analogue scale) at three days postpartum (RR 0.71, 95% CI 0.48 to 1.05, one trial, 165 participants, very low-certainty evidence). There is probably little or no difference for long-term (six months or more) dyspareunia (RR1.14, 95% CI 0.84 to 1.53, three trials, 1107 participants, moderate-certainty evidence); and there may be little or no difference for long-term (six months or more) urinary incontinence (average RR 0.98, 95% CI 0.67 to 1.44, three trials, 1107 participants, low-certainty evidence). One trial reported genital prolapse at three years postpartum. There was no clear difference between the two groups (RR 0.30, 95% CI 0.06 to 1.41; 365 women; one trial, low certainty evidence). Other outcomes relating to long-term effects were not reported (urinary fistula, rectal fistula, and faecal incontinence). Subgroup analyses by parity (primiparae versus multiparae) and by surgical method (midline versus mediolateral episiotomy) did not identify any modifying effects. Pain was not well assessed, and women's preferences were not reported.One trial examined selective episiotomy compared with routine episiotomy in women where an operative vaginal delivery was intended in 175 women, and did not show clear difference on severe perineal trauma between the restrictive and routine use of episiotomy, but the analysis was underpowered.

Authors' conclusions: In women where no instrumental delivery is intended, selective episiotomy policies result in fewer women with severe perineal/vaginal trauma. Other findings, both in the short or long term, provide no clear evidence that selective episiotomy policies results in harm to mother or baby.The review thus demonstrates that believing that routine episiotomy reduces perineal/vaginal trauma is not justified by current evidence. Further research in women where instrumental delivery is intended may help clarify if routine episiotomy is useful in this particular group. These trials should use better, standardised outcome assessment methods.

PubMed Disclaimer

Conflict of interest statement

Hong Jiang received support from the Effective Health care Research Consortium, funded by UK aid from the UK government for the benefit of developing countries (Grant: 5242) ‐ this award was paid to Hong Jiang's institution and was used to support the preparation of this review.

Xu Qian received support from the Effective Health care Research Consortium, funded by UK aid from the UK government for the benefit of developing countries (Grant: 5242) ‐ this award was paid to Xu Qian's institution and was used to support the preparation of this review.

Guillermo Carroli is the principal investigator on a large trial included in this review. Risk of bias assessment, data extraction were carried out by authors independent of GC. PG provided oversight on expression of data from this trial and interpretation of its findings with regard to this potential conflict of interest.

Paul Garner is the Director of the Effective Health Care Research Programme Consortium, a DFID funded research programme that aims to increase the number of decisions in low and middle income countries based on reliable evidence.

Figures

1
1
The rationale commonly used to justify routine episiotomy
2
2
Study flow diagram
3
3
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies
4
4
Risk of bias summary: review authors' judgements about each risk of bias item for each included study
5
5
Funnel plot of comparison: 1 Restrictive versus routine episiotomy (planned non‐instrumental), outcome: 1.1 Severe perineal/vaginal trauma
1.1
1.1. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 1 Severe perineal/vaginal trauma.
1.2
1.2. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 2 Severe perineal/vaginal trauma (grouped by trial implementation success).
1.3
1.3. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 3 Blood loss at delivery (mL).
1.4
1.4. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 4 Newborn Apgar score < 7 at 5 minutes.
1.5
1.5. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 5 Perineal infection.
1.6
1.6. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 6 Moderate or severe pain (visual analogue scale).
1.7
1.7. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 7 Dyspareunia long term (≥ 6 m).
1.8
1.8. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 8 Genital prolapse long term (≥ 6 m).
1.9
1.9. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 9 Urinary incontinence long term (≥ 6 m).
1.10
1.10. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 10 Need for perineal suturing.
1.11
1.11. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 11 Admission to special care baby unit.
1.12
1.12. Analysis
Comparison 1 Restrictive versus routine episiotomy (where non‐instrumental was intended), Outcome 12 Pain at different time points (any measure).
2.1
2.1. Analysis
Comparison 2 Restrictive versus routine episiotomy (non‐instrumental, subgroup by parity), Outcome 1 Severe perineal/vaginal trauma.
3.1
3.1. Analysis
Comparison 3 Restrictive versus routine episiotomy (non‐instrumental, subgroup midline‐midlateral), Outcome 1 Severe vaginal/perineal trauma.
4.1
4.1. Analysis
Comparison 4 Restrictive versus routine episiotomy (operative vaginal birth was intended), Outcome 1 Severe perineal/vaginal trauma.
4.2
4.2. Analysis
Comparison 4 Restrictive versus routine episiotomy (operative vaginal birth was intended), Outcome 2 Apgar < 7 at 5 minutes.
4.3
4.3. Analysis
Comparison 4 Restrictive versus routine episiotomy (operative vaginal birth was intended), Outcome 3 Perineal infection.
4.4
4.4. Analysis
Comparison 4 Restrictive versus routine episiotomy (operative vaginal birth was intended), Outcome 4 Moderate/severe dyspareunia long term (≥ 6 m).
4.5
4.5. Analysis
Comparison 4 Restrictive versus routine episiotomy (operative vaginal birth was intended), Outcome 5 Urinary incontinence long term (≥ 6 m).
4.6
4.6. Analysis
Comparison 4 Restrictive versus routine episiotomy (operative vaginal birth was intended), Outcome 6 Admission to special care baby unit.

Update of

References

References to studies included in this review

Ali 2004 {published data only}
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References to studies excluded from this review

Amorim 2015 {published data only}
    1. Amorim MMR, Neto AHF, Katz L, Coutinho I, Melo I, Leal NV. Selective episiotomy compared with implementation of a nonepisiotomy protocol. A randomized clinical trial. Obstetrics & Gynecology 2015;125(5 Suppl):41S‐42S.
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Karbanova 2013 {published data only}
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Swift 2014 {published data only}
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References to ongoing studies

NCT02356237 {published data only}
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