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Review
. 2017 Sep;31(9).
doi: 10.1002/bmc.3945. Epub 2017 Feb 27.

Application of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4 D): An update

Abdalla A Elbashir  1   2 , Oliver J Schmitz  2 , Hassan Y Aboul-Enein  3
Affiliations
Review

Application of capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4 D): An update

Abdalla A Elbashir et al. Biomed Chromatogr. 2017 Sep.

Abstract

Capacitively coupled contactless conductivity detection (C4 D) has appeared as a powerful technique for the detection of compounds lacking chromogenic or fluorogenic group. Since our last review (Biomedical Chromatography 2014; 28: 1502-1506) several new capillary electrophoresis (CE)-C4 D methods have been reported. This review provides an update of the most recent utilization of CE-C4 D in the field of pharmaceutical, biomedical and food analysis covering the period from February 2014 to October 2016. The use of CE with C4 D in the pharmaceutical field has been shown in many papers. Examples illustrate the applicability of CE-C4 D in the fields of pharmaceutical, biomedical and food analysis. Finally, general conclusions and perspectives are provided.

Keywords: biomedical analysis; capacitively coupled contactless conducuctivity; capillary electrophoresis; pharmaceutical analysis.

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