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Comment
. 2017 Feb 7;25(2):213.
doi: 10.1016/j.str.2017.01.009.

Seeing HPV in the New Light Offers a Glimpse of Heparin

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Seeing HPV in the New Light Offers a Glimpse of Heparin

Peter C Angeletti. Structure. .
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Abstract

In this issue of Structure, Guan et al. (2017) describe cryo-EM mapping of human papillomavirus 16 (HPV16) capsids that propose locations for L2 and heparin binding sites. The high resolution of the modern cryo-EM methods (in this case down to 4.3 Å) opens great opportunities to probe conformational changes that take place during virus-receptor binding.

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