Young and Lean: Elimination of Senescent Cells Boosts Adaptive Thermogenesis
- PMID: 28178562
- DOI: 10.1016/j.cmet.2017.01.012
Young and Lean: Elimination of Senescent Cells Boosts Adaptive Thermogenesis
Abstract
Thermogenesis converts the chemical energy of nutrients into heat, and this is associated to improved metabolic performance. In a previous issue of Cell Metabolism, Berry et al. (2017) reported that the progenitors of thermogenic beige adipocytes lose functionality with aging, and this process can be reversed with strategies that eliminate senescent cells.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans.Cell Metab. 2017 Jan 10;25(1):166-181. doi: 10.1016/j.cmet.2016.10.023. Epub 2016 Nov 23. Cell Metab. 2017. PMID: 27889388 Free PMC article.
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