Microbial Molecules from the Multitudes within Us
- PMID: 28178564
- DOI: 10.1016/j.cmet.2017.01.013
Microbial Molecules from the Multitudes within Us
Abstract
Chemists demonstrate in Cell that intestinal microbes are capable of synthesizing metabolites that look like clinical drugs and inhibit human targets. These results provide molecular resolution to the field of mammalian-microbial mutualism and highlight the potential for natural product discovery from the multitudes within us.
Keywords: GI microbiota; Koch’s Postulates; human microbiome; human therapeutics; microbial metabolites; natural products.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
-
Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.Cell. 2017 Jan 26;168(3):517-526.e18. doi: 10.1016/j.cell.2016.12.021. Epub 2017 Jan 19. Cell. 2017. PMID: 28111075 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
