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Comment
. 2017 Apr;40(4):351-352.
doi: 10.1038/hr.2017.7. Epub 2017 Feb 9.

Intrarenal renin-angiotensin system activation in end-stage renal disease

Affiliations
Comment

Intrarenal renin-angiotensin system activation in end-stage renal disease

Maki Urushihara et al. Hypertens Res. 2017 Apr.
No abstract available

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Conflict of interest statement

CONFLICT OF INTEREST

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic of the renin-angiotensin system in renal damage. ACE, angiotensin converting enzyme; AGT, angiotensinogen; Ang, angiotensin; AT1R, angiotensin type 1 receptor; (P)RR, (pro)renin receptor.

Comment on

References

    1. Kobori H, Urushihara M. Augmented intrarenal and urinary angiotensinogen in hypertension and chronic kidney disease. Pflugers Arch. 2013;465:3–12. - PMC - PubMed
    1. Navar LG. Intrarenal renin-angiotensin system in regulation of glomerular function. Curr Opin Nephrol Hypertens. 2014;23:38–45. - PMC - PubMed
    1. Urushihara M, Kagami S. Role of the intrarenal renin-angiotensin system in the progression of renal disease. Pediatr Nephrol. doi: 10.1007/s00467-016-3449-7. e-pub ahead of print 5 July 2016. - DOI - PubMed
    1. Kobori H, Nangaku M, Navar LG, Nishiyama A. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev. 2007;59:251–287. - PubMed
    1. Henrich WL, McAllister EA, Eskue A, Miller T, Moe OW. Renin regulation in cultured proximal tubular cells. Hypertension. 1996;27:1337–1340. - PubMed

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