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Case Reports
. 2017 Jan 19:20:1-3.
doi: 10.1016/j.gore.2017.01.006. eCollection 2017 May.

Proposed novel nomenclature of vulvar smooth muscle tumors; a case of Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) of the vulva

Mathieu Viau  1 , Marie Plante  2 , Marie-Claude Renaud  2 , Katherine Grondin  3 , Chantale Morin  3
Affiliations
Case Reports

Proposed novel nomenclature of vulvar smooth muscle tumors; a case of Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) of the vulva

Mathieu Viau et al. Gynecol Oncol Rep. .

Abstract

•Clinical experience with smooth muscle tumors of the vulva is limited.•Some tumors present ambiguous histological features concerning for malignancy.•These include infiltration, mitotic activity, size, atypia and tumor cell necrosis.•A case of smooth muscle tumor of the vulva with cellular atypia is presented.•"Smooth Muscle Tumor of Uncertain Malignant Potential" of the vulva is advocated.

Keywords: Cytologic atypia; Leiomyoma; Leiomyosarcoma; Smooth Muscle Tumor of Uncertain Malignant Potential; Smooth muscle tumor; Vulva.

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Figures

Fig. 1
Fig. 1
Pelvic MRI showing the bilobed lesion (arrow) in the right labium majus.
Fig. 2
Fig. 2
Tumor with fascicular architecture (10 ×).
Fig. 3
Fig. 3
Spindle-shaped cells with nuclear atypia (40 ×).
Fig. 4
Fig. 4
Tumor was positive for Caldesmon (10 ×).
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References

    1. Bell S.W., Kempson R.L., Hendrickson M.R. Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am. J. Surg. Pathol. 1994;18:535–558. - PubMed
    1. Clement P.B. The pathology of uterine smooth muscle tumors and mixed endometrial stromal-smooth muscle tumors: a selective review with emphasis on recent advances. Int. J. Gynecol. Pathol. 2000;19:39–55. - PubMed
    1. Curtin J.P., Saigo P., Slucher B., Venkatraman E.S., Mychalczak B., Hoskins W.J. Soft-tissue sarcoma of the vagina and vulva: a clinicopathologic study. Obstet. Gynecol. 1995;86:269–272. - PubMed
    1. DiSaia P.J., Pecorelli S. Gynecological sarcomas. Semin. Surg. Oncol. 1994;10:369–373. - PubMed
    1. Mills A.M., Longacre T.A. Smooth muscle tumors of the female genital tract. Surg. Pathol. Clin. 2009;2:625–677. - PubMed

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