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. 2017 Feb 9;8(2):e2604.
doi: 10.1038/cddis.2016.353.

Arginylation: a new regulator of mRNA stability and heat stress response

Kamalakshi Deka  1 , Sougata Saha  1
Affiliations

Arginylation: a new regulator of mRNA stability and heat stress response

Kamalakshi Deka et al. Cell Death Dis. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Protein arginylation plays a protective role during heat stress. (a) Arginylation of an unknown target facilitates HSP mRNA stabilization leading to sustained expression of HSP proteins and cellular protection by maintaining mitochondrial integrity and inhibition of apoptosis. (b) Cells lacking arginylation fails to stabilize HSP mRNA possibly due to absence of arginylation in key protein/s. This causes insufficient level of HSP proteins resulting in weak stress response and cell death
See this image and copyright information in PMC

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