Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Feb;22(5):30456.
doi: 10.2807/1560-7917.ES.2017.22.5.30456.

Swine influenza A (H1N1) virus (SIV) infection requiring extracorporeal life support in an immunocompetent adult patient with indirect exposure to pigs, Italy, October 2016

Affiliations
Case Reports

Swine influenza A (H1N1) virus (SIV) infection requiring extracorporeal life support in an immunocompetent adult patient with indirect exposure to pigs, Italy, October 2016

Francesca Rovida et al. Euro Surveill. 2017 Feb.

Abstract

We describe a case of severe swine influenza A(H1N1) virus infection in an immunocompetent middle-aged man in October 2016 in Italy who had only indirect exposure to pigs. The patient developed a severe acute distress respiratory syndrome which was successfully supported by extracorporeal membrane oxygenation and treated with antiviral therapy. The sole risk factor for influenza was a body mass index > 30 kg/m2. After a month of hospitalisation, the patient was discharged in good health.

Keywords: extracorporeal membrane oxygenation; influenza virus; respiratory infection.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Chest X-ray and computed tomography in a patient with severe swine influenza A(H1N1), Italy, October 2016
Figure 2
Figure 2
Phylogenetic relationship of human and swine influenza A(H1N1) virus strains based on complete haemagglutinin and neuraminidase nucleotide sequences, compared with patient isolate, Italy, October 2016

Comment in

References

    1. Piralla A, Baldanti F, Gerna G. Phylogenetic patterns of human respiratory picornavirus species, including the newly identified group C rhinoviruses, during a 1-year surveillance of a hospitalized patient population in Italy. J Clin Microbiol. 2011;49(1):373-6. 10.1128/JCM.01814-10 - DOI - PMC - PubMed
    1. World Health Organization (WHO). CDC protocol of realtime RTPCR for influenza A(H1N1). Geneva: WHO; 2009. [Accessed: 15 Dec 2009]. Available from: http://www.who.int/csr/resources/publications/swineflu/CDCRealtimeRTPCR_...
    1. Hoffmann E, Stech J, Guan Y, Webster RG, Perez DR. Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol. 2001;146(12):2275-89. 10.1007/s007050170002 - DOI - PubMed
    1. Lycett SJ, Baillie G, Coulter E, Bhatt S, Kellam P, McCauley JW, et al. Estimating reassortment rates in co-circulating Eurasian swine influenza viruses. J Gen Virol. 2012;93(Pt 11):2326-36. 10.1099/vir.0.044503-0 - DOI - PMC - PubMed
    1. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013;30(12):2725-9. 10.1093/molbev/mst197 - DOI - PMC - PubMed

Publication types

MeSH terms

Substances