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Case Reports
. 2017 Feb 9:2017:bcr2016218330.
doi: 10.1136/bcr-2016-218330.

Pituitary tuberculoma with subsequent drug-resistant tuberculous lymphadenopathy: an uncommon presentation of a common disease

Geethu Antony  1 , Riddhi Dasgupta  2 , Geetha Chacko  1 , Nihal Thomas  2
Affiliations
Case Reports

Pituitary tuberculoma with subsequent drug-resistant tuberculous lymphadenopathy: an uncommon presentation of a common disease

Geethu Antony et al. BMJ Case Rep. .

Abstract

We report a case of pituitary tuberculosis which presented as a non-functioning pituitary macroadenoma, and subsequently developed multidrug-resistant tuberculous lymphadenopathy. Pituitary tuberculosis continues to be a rare presentation of tuberculosis, but incidence and prevalence are expected to grow with increasing numbers of multidrug-resistant tuberculosis. Isolated pituitary tuberculosis is rare. Tuberculosis should be considered in the differential diagnosis in evaluation of a sellar mass.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
(A) T1-weighted coronal MRI image of brain showing an isointense mass in the pituitary region extending in to the suprasellar region. (B) Post contrast T1-weighted coronal image of brain showing contrast enhancement of the lesion. The normal pituitary is not seen separately.
Figure 2
Figure 2
(A) Histopathology of the sellar mass showing caseating granulomatous inflammation. (B) High-power image of the same lesion showing multinucleate giant cell of langerhans cell type.
Figure 3
Figure 3
Histopathology of the cervical lymph node showing caseating granulomatous inflammation.
Figure 4
Figure 4
Follow-up MRI image—post contrast T1-weighted coronal image of the brain showing postoperative changes in sellar floor and thin rim of pituitary gland along the floor and normal pituitary stalk.
See this image and copyright information in PMC

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