Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Jan 27:6:80.
doi: 10.12688/f1000research.10117.1. eCollection 2017.

Novel approaches for treating hypertension

Andrew J Freeman  1 , Antony Vinh  1 , Robert E Widdop  1
Affiliations
Review

Novel approaches for treating hypertension

Andrew J Freeman et al. F1000Res. .

Abstract

Hypertension, or high blood pressure, is a prevalent yet modifiable risk factor for cardiovascular disease. While there are many effective treatments available to combat hypertension, patients often require at least two to three medications to control blood pressure, although there are patients who are resistant to such therapies. This short review will briefly update on recent clinical advances and potential emerging therapies and is intended for a cross-disciplinary readership.

Keywords: cardiovascular disease; high blood pressure; hypertension; hypertension therapies.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests No competing interests were disclosed. No competing interests were disclosed.

References

    1. James PA, Oparil S, Carter BL, et al. : 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311(5):507–20. 10.1001/jama.2013.284427 - DOI - PubMed
    1. Neal B, MacMahon S, Chapman N, et al. : Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Blood Pressure Lowering Treatment Trialists' Collaboration. Lancet. 2000;356(9246):1955–64. 10.1016/S0140-6736(00)03307-9 - DOI - PubMed
    1. Psaty BM, Smith NL, Siscovick DS, et al. : Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis. JAMA. 1997;277(9):739–45. 10.1001/jama.1997.03540330061036 - DOI - PubMed
    1. SPRINT Research Group, . Wright JT, Jr, Williamson JD, et al. : A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2015;373(22):2103–16. 10.1056/NEJMoa1511939 - DOI - PMC - PubMed

    2. F1000 Recommendation

    1. Cushman WC, Whelton PK, Fine LJ, et al. : SPRINT Trial Results: Latest News in Hypertension Management. Hypertension. 2016;67(2):263–5. 10.1161/HYPERTENSIONAHA.115.06722 - DOI - PMC - PubMed

LinkOut - more resources