Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Jan 27:6:81.
doi: 10.12688/f1000research.10020.1. eCollection 2017.

Recent Advances in Endometrial Cancer

Arthur-Quan Tran  1 , Paola Gehrig  1
Affiliations
Review

Recent Advances in Endometrial Cancer

Arthur-Quan Tran et al. F1000Res. .

Abstract

Endometrial cancer is the most common gynecologic malignancy in the United States, with yearly rates continuing to increase. Most women present with early stage disease; however, advanced disease carries a grave prognosis. As a result, novel therapies are currently under investigation for the treatment of endometrial cancer. These advances include a better understanding of the genetic basis surrounding the development of endometrial cancer, novel surgical therapies, and new molecular targets for the treatment of this disease. This review explores the literature regarding these advancements in endometrial cancer.

Keywords: endometrial cancer; molecular targets; surgical therapies; treatment.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests. No competing interests were disclosed. No competing interests were disclosed.

References

    1. American Cancer Society: Cancer Facts & Figures 2016. Cancer Facts Fig 2016.2016;1–9. Reference Source
    1. SEER Stat Fact Sheets: Endometrial Cancer. 2016; Accessed April 10, 2016. Reference Source
    1. Bokhman JV: Two pathogenetic types of endometrial carcinoma. Gynecol Oncol. 1983;15(1):10–7. 10.1016/0090-8258(83)90111-7 - DOI - PubMed
    1. Basil JB, Goodfellow PJ, Rader JS, et al. : Clinical significance of microsatellite instability in endometrial carcinoma. Cancer. 2000;89(8):1758–64. 10.1002/1097-0142(20001015)89:8<1758::AID-CNCR16>3.0.CO;2-A - DOI - PubMed
    1. Bilbao C, Rodriguez G, Ramirez R, et al. : The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer. Int J Cancer. 2006;119(3):563–70. 10.1002/ijc.21862 - DOI - PubMed