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Case Reports
. 2017:2017:6176372.
doi: 10.1155/2017/6176372. Epub 2017 Jan 16.

Morquio's Syndrome: A Case Report of Two Siblings

Sathish Muthukumar Ramalingam  1 , Daya Srinivasan  2 , Sandhya ArunKumar  1 , Joe Louis ChiriyanKandath  2 , Sriram Kaliamoorthy  1
Affiliations
Case Reports

Morquio's Syndrome: A Case Report of Two Siblings

Sathish Muthukumar Ramalingam et al. Case Rep Dent. 2017.

Abstract

Morquio syndrome or MPS IVA is a rare type of lysosomal storage disease associated with highly specific dental abnormalities. We present two siblings with enamel hypoplasia and skeletal abnormalities. A diagnosis of mucopolysaccharidosis type IVA was reached based on the clinical, radiographic, and dental findings of the patients. The dental findings are useful diagnostic aid for the early diagnosis of this debilitating disorder.

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Conflict of interest statement

There are no competing interests.

Figures

Figure 1
Figure 1
(a), (b) Spade-shaped incisors, pointed cusps, and spacing between teeth in case 1. (c) Orthopantomograph showing thin enamel with normal radio density. (d) Spinal radiographs revealing kyphoscoliosis and tongue-like projections from anterior surface of vertebral bodies in case 1.
Figure 2
Figure 2
(a), (b) Spade-shaped incisors, pointed cusps, and spacing between teeth in both maxillary and mandibular teeth in case 2. (c) Orthopantomograph showing thin enamel with normal radio density. (d) Pelvic radiograph showing shallow acetabula and square-shaped femoral head in case 2.
See this image and copyright information in PMC

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