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Case Reports
. 2017:2017:5245904.
doi: 10.1155/2017/5245904. Epub 2017 Jan 17.

Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody

Praneet Iyer  1 , Ahmed Dirweesh  2 , Ritika Zijoo  2
Affiliations
Case Reports

Hydralazine Induced Lupus Syndrome Presenting with Recurrent Pericardial Effusion and a Negative Antinuclear Antibody

Praneet Iyer et al. Case Rep Rheumatol. 2017.

Abstract

Drug induced lupus erythematosus (DIL or DILE) is an autoimmune disorder caused by chronic use of certain drugs. We report a unique case of hydralazine induced lupus syndrome (HILS) with a negative antinuclear antibody in a female patient who was on hydralazine for a period of 1.5-2 years and developed recurrent pericardial effusion as a result of it. Initially her condition was managed with a pericardial window. The recurrence of a massive pericardial effusion necessitated a right hemipericardiectomy. After hydralazine was stopped, she never had any further episodes of pericardial effusion or tamponade.

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Conflict of interest statement

All authors declared no competing interests.

Figures

Figure 1
Figure 1
Axial CT chest showing a large pericardial effusion with a small left pleural effusion.
See this image and copyright information in PMC

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