Psychosocial interventions for supporting women to stop smoking in pregnancy
- PMID: 28196405
- PMCID: PMC6472671
- DOI: 10.1002/14651858.CD001055.pub5
Psychosocial interventions for supporting women to stop smoking in pregnancy
Abstract
Background: Tobacco smoking remains one of the few preventable factors associated with complications in pregnancy, and has serious long-term implications for women and babies. Smoking in pregnancy is decreasing in high-income countries, but is strongly associated with poverty and is increasing in low- to middle-income countries.
Objectives: To assess the effects of smoking cessation interventions during pregnancy on smoking behaviour and perinatal health outcomes.
Search methods: In this sixth update, we searched the Cochrane Pregnancy and Childbirth Group's Trials Register (13 November 2015), checked reference lists of retrieved studies and contacted trial authors.
Selection criteria: Randomised controlled trials, cluster-randomised trials, and quasi-randomised controlled trials of psychosocial smoking cessation interventions during pregnancy.
Data collection and analysis: Two review authors independently assessed trials for inclusion and trial quality, and extracted data. Direct comparisons were conducted in RevMan, with meta-regression conducted in STATA 14.
Main results: The overall quality of evidence was moderate to high, with reductions in confidence due to imprecision and heterogeneity for some outcomes. One hundred and two trials with 120 intervention arms (studies) were included, with 88 trials (involving over 28,000 women) providing data on smoking abstinence in late pregnancy. Interventions were categorised as counselling, health education, feedback, incentives, social support, exercise and dissemination.In separate comparisons, there is high-quality evidence that counselling increased smoking cessation in late pregnancy compared with usual care (30 studies; average risk ratio (RR) 1.44, 95% confidence interval (CI) 1.19 to 1.73) and less intensive interventions (18 studies; average RR 1.25, 95% CI 1.07 to 1.47). There was uncertainty whether counselling increased the chance of smoking cessation when provided as one component of a broader maternal health intervention or comparing one type of counselling with another. In studies comparing counselling and usual care (largest comparison), it was unclear whether interventions prevented smoking relapse among women who had stopped smoking spontaneously in early pregnancy. However, a clear effect was seen in smoking abstinence at zero to five months postpartum (11 studies; average RR 1.59, 95% CI 1.26 to 2.01) and 12 to 17 months (two studies, average RR 2.20, 95% CI 1.23 to 3.96), with a borderline effect at six to 11 months (six studies; average RR 1.33, 95% CI 1.00 to 1.77). In other comparisons, the effect was unclear for most secondary outcomes, but sample sizes were small.Evidence suggests a borderline effect of health education compared with usual care (five studies; average RR 1.59, 95% CI 0.99 to 2.55), but the quality was downgraded to moderate as the effect was unclear when compared with less intensive interventions (four studies; average RR 1.20, 95% CI 0.85 to 1.70), alternative interventions (one study; RR 1.88, 95% CI 0.19 to 18.60), or when smoking cessation health education was provided as one component of a broader maternal health intervention.There was evidence feedback increased smoking cessation when compared with usual care and provided in conjunction with other strategies, such as counselling (average RR 4.39, 95% CI 1.89 to 10.21), but the confidence in the quality of evidence was downgraded to moderate as this was based on only two studies and the effect was uncertain when feedback was compared to less intensive interventions (three studies; average RR 1.29, 95% CI 0.75 to 2.20).High-quality evidence suggests incentive-based interventions are effective when compared with an alternative (non-contingent incentive) intervention (four studies; RR 2.36, 95% CI 1.36 to 4.09). However pooled effects were not calculable for comparisons with usual care or less intensive interventions (substantial heterogeneity, I2 = 93%).High-quality evidence suggests the effect is unclear in social support interventions provided by peers (six studies; average RR 1.42, 95% CI 0.98 to 2.07), in a single trial of support provided by partners, or when social support for smoking cessation was provided as part of a broader intervention to improve maternal health.The effect was unclear in single interventions of exercise compared to usual care (RR 1.20, 95% CI 0.72 to 2.01) and dissemination of counselling (RR 1.63, 95% CI 0.62 to 4.32).Importantly, high-quality evidence from pooled results demonstrated that women who received psychosocial interventions had a 17% reduction in infants born with low birthweight, a significantly higher mean birthweight (mean difference (MD) 55.60 g, 95% CI 29.82 to 81.38 g higher) and a 22% reduction in neonatal intensive care admissions. However the difference in preterm births and stillbirths was unclear. There did not appear to be adverse psychological effects from the interventions.The intensity of support women received in both the intervention and comparison groups has increased over time, with higher-intensity interventions more likely to have higher-intensity comparisons, potentially explaining why no clear differences were seen with increasing intervention intensity in meta-regression analyses. Among meta-regression analyses: studies classified as having 'unclear' implementation and unequal baseline characteristics were less effective than other studies. There was no clear difference between trials implemented by researchers (efficacy studies), and those implemented by routine pregnancy staff (effectiveness studies), however there was uncertainty in the effectiveness of counselling in four dissemination trials where the focus on the intervention was at an organisational level. The pooled effects were similar in interventions provided for women classified as having predominantly low socio-economic status, compared to other women. The effect was significant in interventions among women from ethnic minority groups; however not among indigenous women. There were similar effect sizes in trials with biochemically validated smoking abstinence and those with self-reported abstinence. It was unclear whether incorporating use of self-help manuals or telephone support increased the effectiveness of interventions.
Authors' conclusions: Psychosocial interventions to support women to stop smoking in pregnancy can increase the proportion of women who stop smoking in late pregnancy and the proportion of infants born low birthweight. Counselling, feedback and incentives appear to be effective, however the characteristics and context of the interventions should be carefully considered. The effect of health education and social support is less clear. New trials have been published during the preparation of this review and will be included in the next update.
Conflict of interest statement
Catherine Chamberlain is receiving an Australian National Health and Medical Research Council Early Career Fellowship (1088813). She was also awarded an NIHR Cochrane Review Incentive Scheme award (15/81/18) to support the preparation of this updated review. Catherine Chamberlain is also an author on the Cochrane Review entitled 'Pharmacological Interventions to promote smoking cessation in pregnancy" (Coleman 2015).
Alison O'Mara‐Eves: none known.
Jessie Porter: none known.
Tim Coleman has, in received awards from NIHR, HTA and NIHR paid to his institution. These awards have been used to run research projects. He has also received a single payment from Pierre Fabre Laboratories, France, for speaking at an educational meeting arranged by Pierre Fabre Laboratories (who are manufacturers of nicotine replacement therapy). PFL are a manufacturer of transdermal nicotine patches ‐ the content of the presentation was not vetted and no attempt was made to influence the content of the presentation. Tim Colemans is also an author and contact person for the Cochrane Review entitled 'Pharmacological Interventions to promote smoking cessation in pregnancy" (Coleman 2015).
Susan M Perlen: none known.
James Thomas: none known.
Joanne E McKenzie: none known.
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- Windsor RA. The efficacy and cost‐effectiveness of smoking cessation methods for pregnant women. Southern Medical Journal. 1986; Vol. 79;p34.
Windsor 1985 (AvC) {published data only}
-
- Windsor RA. The efficacy and cost‐effectiveness of smoking cessation methods for pregnant women. Southern Medical Journal 1986;79(9 Suppl):34.
Windsor 1993 {published data only}
-
- Windsor RA. The efficacy and cost‐effectiveness of smoking cessation methods for pregnant women. Southern Medical Journal 1986;79(9 Suppl):34.
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- Windsor RA, Contreras L, Artz L, Lowe JB. Smoking cessation and pregnancy intervention trial: preliminary mid‐trial results. Progress in Clinical and Biological Research 1990;339:107‐17. - PubMed
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- Windsor RA, Li CQ, Boyd NR, Hartmann KE. The use of significant reduction rates to evaluate health education methods for pregnant smokers: a new harm reduction behavioural indicator. Health Education and Behavior 1999;26:648‐61. - PubMed
Windsor 2011 {published data only}
-
- Windsor R, Clark J, Cleary S, Davis A, Thorn S, Abroms L, et al. Effectiveness of the smoking cessation and reduction in pregnancy treatment (SCRIPT) dissemination project: a science to prenatal care practice partnership. Maternal & Child Health Journal 2014;18(1):180‐90. - PubMed
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- Windsor R, Cleary S, Ramiah K, Clark J, Abroms L, Davis A. The smoking cessation and reduction in pregnancy treatment (SCRIPT) adoption scale: evaluating the diffusion of a tobacco treatment innovation to a statewide prenatal care program and providers. Journal of Health Communication 2013;18(10):1201‐20. - PubMed
References to studies excluded from this review
Albrecht 2011 {published data only}
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- Albrecht S, Kelly‐Thomas K, Osborne JW, Ogbagaber S. The SUCCESS program for smoking cessation for pregnant women. Journal of Obstetric Gynecologic and Neonatal Nursing 2011;40:520‐31. - PubMed
Andrews 2007 {published data only}
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- Andrews JO, Bentley G, Crawford S, Pretlow L, Tingen MS. Using community‐based participatory research to develop a culturally sensitive smoking cessation intervention with public housing neighbourhoods. Ethnicity and Disease 2007;17:326‐31. - PubMed
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- Andrews JO, Felton G, Wewers ME, Waller J, Tingen M. The effect of a multi‐component smoking cessation intervention in African American women residing in public housing. Research in Nursing and Health 2007;30:45‐60. - PubMed
Boshier 2003 {published data only}
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- Boshier A, Wilton LV, Shakir SAW. Evaluation of the safety of bupropion (Zyban) for smoking cessation from experience gained in general practice use in England in 2000. European Journal of Clinical Pharmacology 2003;59:767‐73. - PubMed
Bowden 2010 {published data only}
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- Bowden JA, Oag DA, Smith KL, Miller CI. An integrated brief intervention to address smoking in pregnancy. Acta Obstetricia et Gynecologica 2010;89:496‐504. - PubMed
Brandon 2012 {published and unpublished data}
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- Lopez E, Simmons MAV, Meade C, Quinn G, Pedraza J, Brandon T. The elusive pregnant ex‐smoker: lessons from recruitment for a clinical trial. Society for Research on Nicotine and Tobacco 11th Annual Meeting; 2005 20‐23 March; Prague, Czech Republic. 2005.
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- Quinn G, Ellison BB, Meade C, Roach CN, Lopez E, Albrecht T, et al. Adapting smoking relapse‐prevention materials for pregnant and postpartum women: formative research. Maternal and Child Health Journal 2006;10(3):235‐45. - PubMed
Britton 2006 {published data only}
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- Britton GRA, Brinthaupt J, Stehle JM, James GD. The effectiveness of a nurse‐managed perinatal smoking cessation program implemented in a rural county. Nicotine and Tobacco Research 2006;8(1):13‐28. - PubMed
Britton 2013 {published data only}
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- Britton GR, James GD, Collier R, Sprague LM, Brinthaupt J. The effects of smoking cessation and a programme intervention on birth and other perinatal outcomes among rural pregnant smokers. Annals of Human Biology 2013;40(3):256‐65. - PubMed
Chan 2005 {published data only}
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- Chan B, Einarson A, Koren G. Effectiveness of bupropion for smoking cessation during pregnancy. Journal of Addictive Diseases 2005;24(2):19‐23. - PubMed
Chi 2015 {published data only}
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- Chi YC, Wu CL, Chen CY, Lyu SY, Lo FE, Morisky E. Randomized trial of a secondhand smoke exposure reduction intervention among hospital‐based pregnant women. Addictive Behaviors 2015;41:117‐24. - PubMed
Coleman 2007 {published data only}
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- Coleman T. Double‐blind, randomised, placebo‐controlled trial of nicotine replacement therapy in pregnancy (ongoing trial). nrr.nhs.uk Date first received: 6 July 2006.
Culp 2007 {published data only}
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- Culp AM, Culp RE, Anderson JW, Carter S. Health and safety intervention with first time mothers. Health Education Research 2007;22(2):285‐94. - PubMed
DeVries 2006 {published data only}
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- Bakker M. Pregnancy: a Window of Opportunity to Quit Smoking! The Development, Implementation and Evaluation of a Minimal Intervention Strategy for Pregnant Women and Partners [thesis]. Netherlands: Maastricht Health Research Institute for Prevention and Care, 2001.
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- Bakker MJ, Vries H, Ausems EMGT. Effectiveness of a multi media smoking cessation and relapse prevention program for pregnant women. 10th World Conference on Tobacco or Health; 1997 August 24‐28; Beijing, China. 1997:111.
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- Bakker MJ, Dolan‐Mullen P, Vries H, Breukelen G. Feasibility of implementation of a Dutch smoking cessation and relapse prevention protocol for pregnant women. Patient Education and Counseling 2003;49(1):35‐43. - PubMed
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- Bakker MJ, Vries H, Dolan Mullen P, Kok G. Predictors of perceiving smoking cessation counselling as a midwife's role: a survey of Dutch midwives. European Journal of Public Health 2005;15(1):39‐42. - PubMed
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- Vries H, Bakker M, Dolan Mullen P, Breukelen G. The effects of smoking cessation counseling by midwives on Dutch pregnant women and their partners. Patient Education and Counseling 2006;63(1‐2):177‐87. - PubMed
Disantis 2010 {published data only}
Dixon 2009 {published data only}
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- Dixon LE, Aimer P, Fletcher L, Guilliland K, Hendry C. Smoke free outcomes with maternity lead maternity carers: An analysis of smoking during pregnancy from the New Zealand College of Midwives Midwifery database 2004 – 2007. New Zealand College of Midwives Journal 2009;40:13‐9.
Edwards 2009 {published data only}
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- Edwards MJ, Geiser T, Chafin C, Weatherby NL, Smith CM. S.M.A.R.T. Mothers are Resisting Tobacco: Prenatal smoking cessation in WIC mothers. Journal of Allied Health 2009;38(3):170‐6. - PubMed
El‐Mohandes 2013 {published data only}
Emmons 2000 {published data only}
Ershoff 1983 {published data only}
Everett‐Murphy 2010 {published data only}
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- Everett‐Murphy K, Steyn K, Mathews C, Petersen Z, Odendaal H, Gwebushe N, et al. The effectiveness of adapted, best practice guidelines for smoking cessation couseling with disadvantaged, pregnant smokers attending public sector antenatal clinics in Cape Town, South Africa. Acta Obstetricia et Gynecologica 2010;89:478‐89. - PubMed
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- Petersen Z, Steyn K, Lombard C, Everett K, Emmelin M. Smoking cessation intervention among pregnant women in South Africa. African Journal of Midwifery and Women's Health 2009;3(4):181‐6.
Ferguson 2012 {published data only}
Ferreira‐Borges 2005 {published data only}
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- Ferreira‐Borges C. Effectiveness of a brief counseling and behavioral intervention for smoking cessation in pregnant women. Preventive Medicine 2005;41(1):295‐302. - PubMed
Fish 2011 {published data only}
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- Fish LJ, Lyna P, Denman S, Gordon K, Rocha P, Pollak K. Recruitment and retention of Latinos in a couples‐based smoking cessation trial. Annals of Behavioral Medicine 2011;41 Suppl 1:S118.
French 2007 {published data only}
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- French GM, Groner JA, Wewers ME, Ahijevych K. Staying smoke free: an intervention to prevent postpartum relapse. Nicotine and Tobacco Research 2007;9(6):663‐70. - PubMed
Gadomski 2011 {published data only}
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- Gadomski A, Adams L, Tallman N, Krupa N, Jenkins P. Effectiveness of a combined prenatal and postpartum smoking cessation program. Maternal Child Health Journal 2011;15:188‐97. - PubMed
Gebauer 1998 {published data only}
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- Gebauer C, Chung‐Ying K, Haynes E, Wewers ME. A nurse‐managed smoking cessation intervention during pregnancy. Journal of Obstetric, Gynecologic & Neonatal Nursing 1998;21:47‐53. - PubMed
Gillies 1987 {published data only}
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- Gillies PA, Power FL, Turner ID, Madely R. Successful antismoking interventions in pregnancy‐behaviour change, "clinical indicators" or both?. Proceedings of the 7th World Conference on Tobacco & Health; 1990; Perth, Australia. Perth: Health Department of Western Australia, 1990:952‐8.
Grange 2005 {published data only}
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- Grange G, Borgne A, Ouazana A, Valensi P, L'Hullier JP, Aubin JP. Obstetrical ultrasound screening and motivation to stop smoking [Echographies obstetricales et motivation du tabac]. Journal de Gynécologie, Obstétrique et Biologie de la Reproduction 2005;34(7 Pt 1):674‐8. - PubMed
Hahn 2005 {published data only}
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- Hahn EJ, Rayens MK, Warnick TA, Chirila C, Rasnake RT, Paul TP, et al. A controlled trial of a quit and win contest. American Journal of Health Promotion 2005;20(2):117‐26. - PubMed
Hannover 2008 {published data only}
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- Hannover W, Thyrian JR, Roske K, Grempler J, Rumpf HJ, John U, et al. Smoking cessation and relapse prevention for postpartum women: results from a randomized controlled trial at 6, 12, 18 and 24 months. Addictive Behaviors 2008;34:1‐8. - PubMed
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- Röske K, Hannöver W, Grempler J, Thyrian JR, Rumpf HJ, John U, et al. Post‐partum intention to resume smoking. Health Education Research 2006;21(3):386‐92. - PubMed
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- Röske K, Schumann A, Hannöver W, Grempler J, Thyrian JR, Rumpf HJ, et al. Postpartum smoking cessation and relapse prevention intervention: A structural equation modeling application to behavioral and non‐behavioral outcomes of a randomized controlled trial. Journal of Health Psychology 2008;13(4):556‐68. - PubMed
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- Thyrian JR, Freyer‐Adam J, Hannover W, Roske K, Mentzel F, Kufeld C, et al. Population‐based smoking cessation in women post partum: adherence to motivational interviewing in relation to client characteristics and behavioural outcomes. Midwifery 2010;26(2):202‐10. - PubMed
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- Thyrian JR, Hannover W, Grempler J, Roske K, Ulrich J, Hapke U. An intervention to support postpartum women to quit smoking or remain smoke‐free. Journal of Midwifery & Women's Health 2006;51:45‐50. - PubMed
Hayes 2013 {published data only}
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- Hayes CB, Collins C, O'Carroll H, Wyse E, Gunning M, Geary M, et al. Effectiveness of motivational interviewing in influencing smoking cessation in pregnant and postpartum disadvantaged women. Nicotine and Tobacco Research 2013;15(5):969‐77. - PubMed
Herbert 2011 {published data only}
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- Herbert RJ, Gagnon AJ, O'Loughlin JL, Rennick JE. Testing an empowerment intervention to help parents make homes smoke‐free: A randomized controlled trial. Journal of Community Health 2011;36:650‐7. - PubMed
Higgins 2004 {published data only}
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- Higgins ST, Heil SH, Solomon LJ, Bernstein IM, Lussier JP, Abel RL, et al. A pilot study on voucher‐based incentives to promote abstinence from cigarette smoking during pregnancy and postpartum. Nicotine and Tobacco Research 2004;6(6):1015‐20. - PubMed
Hotham 2006 {published data only}
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- Atkinson E, Hotham L, Baghurst P. Nicotine replacement therapy as an adjunct to smoking cessation counselling in pregnancy ‐ a randomised study to evaluate efficacy in an antenatal clinic setting. Australian and New Zealand Journal of Obstetrics and Gynaecology 2003;43:177.
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- Hotham ED, Gilbert AL, Atkinson ER. A randomised‐controlled pilot study using nicotine patches with pregnant women. Addictive Behaviors 2006;31(4):641‐8. - PubMed
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- Hotham ED, Gilbert AL, Atkinson ER. Case studies of three pregnant smokers and their use of nicotine replacement therapy. Midwifery 2005;21:224‐32. - PubMed
Huang 2013 {published data only}
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- Huang CM, Wu HL, Huang SH, Chien LY, Guo JL. Transtheoretical model‐based passive smoking prevention programme among pregnant women and mothers of young children. European Journal of Public Health 2013;23(5):777‐82. - PubMed
Hymowitz 2006 {published data only}
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- Hymowitz N, Schwab J, Eckholdt H. Pediatric residency training on tobacco. Pediatrics 2001;108(1):e8. - PubMed
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- Hymowitz N, Schwab J, Haddock CK, Pyle S, Moore G, Meshberg S. The pediatric resident training on tobacco project: baseline findings from the parent/guardian tobacco survey. Preventive Medicine 2005;41(1):334‐41. - PubMed
Jaakola 2001 {published data only}
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- Jaakola N, Zahlsen K, Jaakola J. Effects of a population based smoking cessation programme on smoking in pregnancy. European Journal of Public Health 2001;11:446‐9. - PubMed
Jimenez‐Muro 2013 {published data only}
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- Jimenez‐Muro A, Nerin I, Samper P, Marqueta A, Beamonte A, Gargallo P, et al. A proactive smoking cessation intervention in postpartum women. Midwifery 2013;29(3):240‐5. - PubMed
Johnston 2011 {published data only}
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- Johnston V, Thomas DP, McDonnell J, Andrews RM. Maternal smoking and smoking in the household during pregnancy and postpartum: findings from an Indigenous cohort in the Northern Territory. Medical Journal of Australia 2011;194(10):556‐9. - PubMed
Kaper 2006 {published data only}
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- Kaper J, Wagena EJ, Willemsen MC, Schayck CP. A randomized controlled trial to assess the effects of reimbursing the costs of smoking cessation therapy on sustained abstinence. Addiction 2006;101:1656‐61. - PubMed
Kapur 2001 {published data only}
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- Kapur B, Hackman R, Selby P, Klein J, Koren G. Randomized, double blind, placebo‐controlled trial of nicotine replacement therapy in pregnancy. Current Therapeutic Research 2001;62(4):274‐8.
Karatay 2010 {published data only}
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- Karatay G, Kublay G, Emiroglu ON. Effect of motivational interviewing on smoking cessation in pregnant women. Journal of Advanced Nursing 2010;66(6):1328‐37. - PubMed
Kazemi 2012 {published data only}
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- IRCT138809242857N1. The effect of education on reducing passive smoking in pregnant women. en.search.irct.ir/view/1883 Date first received: 3 February 2010.
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- Kazemi A, Ehsanpour S, Nekoei‐Zahraei NS. A randomized trial to promote health belief and to reduce environmental tobacco smoke exposure in pregnant women. Health Education Research 2012;27(1):151‐9. - PubMed
Kientz 2005 {published data only}
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- Kientz E, Kupperschmidt B. KICCS: a successful strategy to promote smoking cessation in women during and post pregnancy. Oklahoma Nurse 2005;50(4):27‐30. - PubMed
Langford 1983 {published data only}
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- Langford ER, Thompson EG, Tripp SC. Smoking and health education during pregnancy: evaluation of a program for women in prenatal classes. Canadian Journal of Public Health 1983;74:285‐9. - PubMed
Lee 2008 {published data only}
Levine 2013 {published data only}
Loke 2005 {published data only}
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- Loke AY, Lam TH. A randomized controlled trial of the simple advice given by obstetricians in Guangzhou, China, to non‐smoking pregnant women to help their husbands quit smoking. Patient Education and Counseling 2005;59(1):31‐7. - PubMed
Lowe 1998a {published data only}
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- Lowe JB, Balanda KP, Clare G. Evaluation of antenatal smoking cessation programs for pregnant women. Australian and New Zealand Journal of Public Health 1998;22:55‐9. - PubMed
Lowe 1998b {published data only}
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- Lowe JB, Balanda KP, Clare G. Evaluation of antenatal smoking cessation programs for pregnant women. Australian and New Zealand Journal of Public Health 1998;22:55‐9. - PubMed
MacArthur 1987 {published and unpublished data}
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- MacArthur C, Knox EG. Stopping smoking in pregnancy and birthweight. The Needs of Parents and Infants: Proceedings of a Symposium. Cambridge: The Health Promotion Trust, 1989:41‐55.
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- MacArthur C, Knox EG, Lancashire RJ. Effects at the age of nine of maternal smoking in pregnancy: experimental and observational findings. BJOG: an international journal of obstetrics and gynaecology 2001;108(1):67‐73. - PubMed
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- MacArthur C, Knox EG, Newton JR. Effect of anti‐smoking health education on infant size at birth: a randomized controlled trial. British Journal of Obstetrics and Gynaecology 1987;94:295‐300. - PubMed
Miller 2003 {published data only (unpublished sought but not used)}
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- Miller H, Ranger‐Moore J, Hingten M. Bupropion sr for smoking cessation in pregnancy: a pilot study [abstract]. American Journal of Obstetrics and Gynecology 2003;189(6 Suppl 1):S133.
Mullen 1997 {published data only}
-
- Mullen PD, DiClemente CC, Bartholomew LK. Project PANDA: The importance of theory and context in a program to help women who stop smoking remain abstinent after pregnancy. In: Bartholomew LK, Parcel GS, Kok G, Gottlieb NH editor(s). Intervention Mapping: A Process for Designing Theory‐ and Evidence‐based Health Promotion Programs. Palo Alto, CA: Mayfield: McGraw‐Hill, 2001:453‐77.
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- Mullen PD, DiClemente CC, Carbonari JP, Micol L, Sockrider MM, Richardson M, et al. Project PANDA maintenance of prenatal smoking abstinence postpartum at 6 weeks, and 3, 6, and 12 months. Annals of Behavioural Medicine 1997;19:130.
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- Mullen PD, Richardson MA, Quinn VP, Ershoff DH. Postpartum return to smoking: who is at risk and when. American Journal of Health Promotion 1997;11(5):323‐30. - PubMed
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- Ruggiero L, Webster K, Peipert JF, Wood C. Identification and recruitment of low‐income pregnant smokers. Who are we missing?. Addictive Behaviours 2003;28:1497‐505. - PubMed
Murray 2008 {published data only}
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- Murray RL, Coleman T, Antoniak M, Stocks J, Fergus A, Brfitton J, et al. The effect of proactively identifying smokers and offering smoking cessation support in primary care populations: a cluster‐randomized trial. Addiction 2008;103(6):998–1006. - PubMed
NCT00507975 {published data only}
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- NCT00507975. Study of Nicotine Patch in Pregnancy (SNIPP). clinicaltrials.gov/show/NCT00507975 Date first received: 25 July 2007.
NCT00744913 {published data only}
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- NCT00744913. Study of nicotine replacement therapy in pregnancy. clinicaltrials.gov/NCT00744913 Date first received: 29 August 2008.
O'Connor 1992 {published data only}
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- O'Connor AM, Benzie RJ, McBride BH, Nadon C, Buhler PL, Dulberg CS, et al. Effectiveness of a pregnancy smoking cessation program. Journal of Obstetric, Gynecologic & Neonatal Nursing 1992;21:385‐92. - PubMed
Oncken 2008 {published data only}
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- Oncken C. Pilot study of nicotine replacement for smoking cessation during pregnancy. ClinicalTrials.gov (http://clinicaltrials.gov) (accessed 31 July 2009) 2009.
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- Oncken C, Dornelas E, Greene J, Sankey H, Glasmann A, Kranzler HR. Nicotine replacement treatment for pregnant smokers. Proceedings of the 70th Annual Scientific Meeting of the College on Problems of Drug Dependence; 2008 June 14‐19; San Juan, Puerto Rico. 2008:143.
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- Oncken C, Morris B, Dornelas E, Kranzler H, Walsh S, Greene J. The efficacy and safety of a fixed versus titrated dosage regimen of nicotine gum for smoking cessation or reduction in pregnancy. American Journal of Obstetrics and Gynecology 2006;195(6 Suppl 1):S89.
Peden 2008 {published data only}
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- Peden AR, Rayens MK, Hall LA, Hahn E, Riker C, Ashford K, et al. Nicotine addiction in pregnancy: preliminary efficacy of a mental health intervention. Addictive Disorders and their Treatment 2008;7(4):179‐89.
Phillips 2012 {published data only}
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- Phillips RM, Merritt TA, Goldstein MR, Job JS, Rudatsikira EM. Prevention of postpartum smoking relapse in mothers of infants in the neonatal intensive care unit. Pediatric Academic Societies' 2010 Annual Meeting; 2010 May 1‐4; Vancouver, Canada. 2010.
Polanska 2011 {published data only}
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- Polanska K, Hanke W, Sobala W, Lowe JB, Jaakkola JJK. Predictors of smoking relapse after delivery: Prospective study in Central Poland. Maternal Child Health Journal 2011;15:579‐86. - PubMed
Pollak 2007 {published data only}
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- NCT00224419. Testing pharmacological therapies for pregnant smokers. clinicaltrials.gov/show/NCT00224419 Date first received: 21 September 2005.
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- Pollak KI, Oncken C, Lipkus IM, Peterson BL, Swamy GK, Pletsch PK, et al. Effectiveness of adding nicotine replacement therapy to cognitive behavioral therapy for smoking cessation in pregnant smokers: the Baby Steps trial. Society for Research on Nicotine and Tobacco 13th Annual Meeting; 2007 Feb 21‐24; Austin, Texas. 2007:25, Abstract no: PA6‐3.
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- Pollak KI, Oncken CA, Lipkus IM, Peterson BL, Swany GK, Pletsch PK, et al. Challenges and solutions for recruiting pregnant smokers into a nicotine replacement therapy trial. Nicotine and Tobacco Research 2006;8(4):547‐54. - PubMed
Pollak 2014 {published data only}
Power 1989 {published data only}
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- Power FL, Gillies PA, Madeley R, Abbott M. Research in an antenatal clinic ‐ the experience of the Nottingham Mothers' Stop Smoking Project. Midwifery 1989;5(3):106‐12. - PubMed
Ratner 1999 {published data only}
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- Ratner PA, Johnson JL, Bottorff JL. Smoking relapse and early weaning among postpartum women: is there an association?. Birth 1999;26(1):76‐82. - PubMed
Reitzel 2010 {published data only}
Rush 1992 {published data only}
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- King J, Eiser JR. A strategy for counselling pregnant smokers. Health Education Journal 1981;40:66‐8.
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- Rush D, Butler NR, Eiser JR, King J, Orme J. A trial of health education aimed to reduce cigarette smoking. Paediatric and Perinatal Epidemiology 1992;6:285‐97. - PubMed
Scott 2000 {published data only}
Shakespeare 1990 {published data only}
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- Shakespeare R. The development and evaluation of a smoking cessation counselling training programme for midwives. Proceedings of the 7th World Conference on Tobacco & Health; 1990; Perth, Australia. Perth: Health Department of Western Australia, 1990:950‐1.
Simmons 2014 {published data only}
Stanton 2004 {published data only}
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- Stanton WR, Lowe JB, Moffatt J, Mar CB. Randomised control trial of a smoking cessation intervention directed at men whose partners are pregnant. Preventive Medicine 2004;38:6‐9. - PubMed
Suplee 2004 {published data only}
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- Suplee PD. The importance of providing smoking relapse counseling during the postpartum hospitalization. Journal of Gynecological and Neonatal Nursing 2005;34(6):703‐12. - PubMed
Sutton 2007 {published data only}
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- Sutton S, Gilbert H. Effectiveness of individually tailored smoking cessation advice letters as an adjunct to telephone counselling and generic self‐help materials: randomized controlled trial. Addiction 2007;102:994‐1000. - PubMed
Valanis 2001 {published data only}
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- Valanis B, Lichtenstein E, Mullooly JP, Labuhn K, Brody K, Severson H, et al. Maternal smoking cessation and relapse prevention during health care visits. American Journal of Preventive Medicine 2001;20(1):1‐8. - PubMed
Valbo 1991 {published data only}
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- Valbo A, Schioldborg P. Smoking cessation in pregnancy: mode of intervention and effect. Acta Obstetricia et Gynecologica Scandinavica 1991;70:309‐13. - PubMed
Velasquez 2014 {published data only}
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- Velasquez MM, Sternberg K. Preventing alcohol and tobacco‐exposed pregnancies in primary care settings: Results of a randomized controlled trial. Alcoholism, Clinical and Experimental Research 2014;38(Suppl 1):343A.
Wadland 2007 {published data only}
Wen 2016 {published data only}
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- Wen X, Higgins ST, Xie C, Epstein LH. Improving public acceptability of using financial incentives for smoking cessation during pregnancy: a randomized controlled experiment. Nicotine & Tobacco Research 2016; Vol. 18, issue 5:913‐8. - PubMed
Wiggins 2004 {published data only}
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- Wiggins M, Oakley A, Roberts I, Turner H, Rajan L, Austerberry H, et al. The social support and family health study: a randomised controlled trial and economic evaluation of two alternative forms of postnatal support for mothers living in disadvantaged inner‐city areas. Health Technology Assessment 2004;8(32):1‐120. - PubMed
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- Wilkinson SA, Miller YD, Watson B. The effects of a woman‐focused, woman‐held resource on preventive health behaviours during pregnancy: the pregnancy pocketbook. Women and Health 2010;50:342‐58. - PubMed
Windsor 2000a {published data only}
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- Crawford MA, Woodby LL, Russell TV, Windsor RA. Using formative evaluation to improve a smoking cessation intervention for pregnant women. Health Communication 2005;17(3):265‐81. - PubMed
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- Hahn EJ, Rayens MK, Warnick TA, Chrila C, Rasnake RT, Paul TP, et al. A controlled trial of a quit and win contest. American Journal of Health Promotion 2005;20:117‐26. - PubMed
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- Windsor RA, Woodby L, Miller T, Hardin JM, Crawford MA, DiClemente CC. Effectiveness of agency for health care policy and research clinical practice guideline and patient education methods for pregnant smokers in medicaid maternity care. American Journal of Obstetrics and Gynecology 2000;182 (1 Pt 1):68‐75. - PubMed
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- Windsor RA, Woodby LL, Crawford MA, Hardin JM. Effectiveness and cost benefit of the smoking cessation or reduction in pregnancy treatment model in Medicaid maternity care. Society for Research on Nicotine and Tobacco 7th Annual Meeting; 2001 March 20‐23; Seattle, Washington. 2001.
Winickoff 2010 {published data only}
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- Winickoff JP, Healey EA, Regan S, Park ER, Cole C, Friebely J, et al. Using the postpartum hospital stay to address mothers' and fathers' smoking: the NEWS study. Pediatrics 2010;125(3):518‐25. - PubMed
Wisborg 1998 {published data only}
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Wisborg 2000 {published data only}
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- Wisborg K. Nicotine patches to pregnant smokers ‐ a randomised study. 1st International Conference of the Society for Research on Nicotine and Tobacco; 1998 August 22‐23; Copenhagen, Denmark. 1998.
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Yilmaz 2006 {published data only}
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- Yilmaz G, Karacan C, Yoney A, Yilmaz T. Brief intervention on maternal smoking: a randomized controlled trial. Child: Care, Health and Development 2006;32(1):73‐9. - PubMed
References to ongoing studies
Accornero 2014 {published data only}
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- Accornero, V. Contingency management for smoking cessation in pregnant minority women. clinicaltrials.gov/show/NCT02195570 Date first received: 16 July 2014.
Althabe 2012 {published data only}
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- Althabe F. A smoking cessation intervention during pregnancy in Argentina and Uruguay. ClinicalTrials.gov (http://clinicaltrials.gov/), 2011 [accessed 21 May 2013].
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Blasco Oliete 2004 {published data only}
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- Blasco Oliete M, Sanz Cuesta T, Girbés Fontana M, Pascual Malanda M, Ortiz Valdepeñas J, Garcia Lopez L. Effectiveness of two health interventions to get pregnant women to give up smoking [Efectividad de dos intervenciones sanitarias para conseguir el abandono del consumo de tabaco]. Atencion Primaria 2004;33(5):277‐83. - PMC - PubMed
Bronshtein 2015 {published data only}
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- Bronshtein, E. Optimizing technology‐delivered interventions for smoking in pregnancy: the mommy check‐up study. clinicaltrials.gov/show/NCT02340624 Date first received 13 January 2015.
Cooper 2015 {published data only}
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- Coleman, T. MiQuit Trial: Tailored Text Messages for Pregnant Women (MiQuit). clinicaltrials.gov/show/NCT02043509. ClinicalTrials.gov (http://clinicaltrials.gov/), Date first received: 14 January 2014.
Everett 2008 {published data only}
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- Everett KD, Debnam KJ, Gwede CK. Smoking behaviors of women and men in a smoking cessation clinical trial during pregnancy. Annals of Behavioral Medicine 2008;35(Suppl 1):S199.
Gleeson 1997 {published data only}
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- Gleeson C, Memon I, Milner M, Baines S. Aspects of antenatal care. Smoking cessation in pregnancy: a multiple contact approach. British Journal of Midwifery 1997;5(9):551‐4.
Higgins 2014 {published data only}
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- Higgins, ST. Financial incentives for smoking cessation among disadvantaged pregnant women. clinicaltrials.gov/show/NCT02210832 Date first received: 31 July 2014.
Lasater 2005 {published data only}
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- Lasater, TM. Reducing ETS exposure of pregnant women and newborns. clinicaltrials.gov/show/NCT00142623 Date first received: 1 September 2005.
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- Lasater, TM. Tailored videos to reduce tobacco smoke exposure among pregnant women and newborns. clinicaltrials.gov/show/NCT00142623 Date first received: 1 September 2005.
Lynagh 2012 {published data only}
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