Diabetic nephropathy; principles of diagnosis and treatment of diabetic kidney disease
- PMID: 28197454
- PMCID: PMC5297588
Diabetic nephropathy; principles of diagnosis and treatment of diabetic kidney disease
Abstract
Diabetes mellitus is a leading epidemic of the present world. It is considered the leading cause of death among end-stage renal disease (ESRD) patients. The complications associated with diabetes mellitus have boosted the number of deaths in the last years. These complications are the result of long lasting effects of diabetes mellitus on the glomerular microvasculature of the kidney. Diabetic nephropathy (DN) develops in patients with several years' medical history of diabetes and renal failure. However, research shows that patients with type 1 diabetes progress early to ESRD as compared to those with type 2. DN is more prevalent in ethnic minorities as compared to other groups in society. There are new and different treatment options available since medical science has progressed due to increased research efforts. Unfortunately, there is no permanent cure. The aim of this article is to explore the research of therapeutic strategies currently in use by medical practitioners in order to increase understanding of DN.
Keywords: Diabetes mellitus; Diabetic nephropathy; End Stage renal disease.
References
-
- US Renal Data System. USRDS 2003 Annual Data Report: atlas of end-stage renal disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 2003.
-
- Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA, Holman RR. Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64) Kidney Int. 2003;63:225–32. - PubMed
-
- Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ. Prevention of incipient diabetic nephropathy by high-dose thiamine and benofotiamine. Diabetes. 2003;52:2110–20. - PubMed
-
- Whaley-Connell A, Sowers JR, McCullough PA, Roberts T, McFarlane SI, Chen SC. et al. Diabetes mellitus and CKD awareness: The Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) Am J Kidney Dis. 2009;4(Suppl 4):S11–21. - PubMed
-
- Randhawa G. Developing culturally competent renal services in the United Kingdom: tackling inequalities in health. Transplant Proc. 2003;35:21–3. - PubMed
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