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Editorial
. 2017 Feb 12;9(2):297-298.
doi: 10.18632/aging.101182.

Deubiquitination in cancer stem cells

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Editorial

Deubiquitination in cancer stem cells

Julia M Fraile et al. Aging (Albany NY). .
No abstract available

Keywords: USP54; carcinogenesis; degradome; metastasis; stem cells; ubiquitin-specific protease.

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Figures

Figure 1
Figure 1. Deubiquitinases regulate stem cell biology
USP54 is overexpressed in intestinal stem cells and promotes colorectal carcinoma progression, probably through the regulation of cancer stem cell properties.

References

    1. Nassar D, Blanpain C. Annu Rev Pathol. 2016;11:47–76. doi: 10.1146/annurev-pathol-012615-044438. - DOI - PubMed
    1. Merlos-Suarez A, et al. Cell Stem Cell. 2011;8:511–524. doi: 10.1016/j.stem.2011.02.020. - DOI - PubMed
    1. Okita Y, Nakayama KI. Cell Stem Cell. 2012;11:728–730. doi: 10.1016/j.stem.2012.11.009. - DOI - PubMed
    1. Komander D, et al. Nat Rev Mol Cell Biol. 2009;10:550–563. doi: 10.1038/nrm2731. - DOI - PubMed
    1. Fraile JM, et al. Oncogene. 2012;31:2373–2388. doi: 10.1038/onc.2011.443. - DOI - PubMed

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