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Review
. 1987 May;17(3):177-90.
doi: 10.1016/0147-619x(87)90026-6.

Kinetoplast DNA minicircles: high-copy-number mitochondrial plasmids

D S Ray
Review

Kinetoplast DNA minicircles: high-copy-number mitochondrial plasmids

D S Ray. Plasmid. 1987 May.

Abstract

The kinetoplast DNA of trypanosomes is a highly unusual network of catenated DNA circles of two kinds: maxicircles, the equivalent of conventional mitochondrial DNA, and minicircles, high-copy-number mitochondrial plasmids with no known function. Kinetoplast minicircles share many features with bacterial plasmids and represent a novel model system for the study of the mechanisms and regulation of DNA replication in eukaryotic organisms.

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