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. 2017 May 1;64(9):1275-1278.
doi: 10.1093/cid/cix125.

Impact of Tenofovir on Hepatitis Delta Virus Replication in the Swiss Human Immunodeficiency Virus Cohort Study

Charles Béguelin  1 , Nicole Friolet  1 , Darius Moradpour  2 , Roland Sahli  3 , Franziska Suter-Riniker  4 , Alexander Lüthi  4 , Matthias Cavassini  5 , Huldrych F Günthard  6   7 , Manuel Battegay  8 , Enos Bernasconi  9 , Patrick Schmid  10 , Alexandra Calmy  11 , Andrew Atkinson  1 , Andri Rauch  1 , Gilles Wandeler  1   12 ; Swiss HIV Cohort Study
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Free article

Impact of Tenofovir on Hepatitis Delta Virus Replication in the Swiss Human Immunodeficiency Virus Cohort Study

Charles Béguelin et al. Clin Infect Dis. .
Free article

Abstract

We analyzed changes in hepatitis B virus and hepatitis delta virus (HDV) viral loads (VL) during tenofovir-containing antiretroviral therapy among patients with a replicating HDV infection in the Swiss HIV Cohort Study. Only 28.6% experienced a ≥2.0 log reduction in HDV RNA, and 14.3% had undetectable HDV VL within 5 years.

Keywords: coinfection; hepatitis delta virus; human immunodeficiency virus; replication; tenofovir.

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