Baring cellular souls

Alex K Shalek¹

Affiliations

Affiliation

¹ Institute for Medical Engineering & Science (IMES) and Department of Chemistry, MIT, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Email: shalek@mit.edu.

PMID: 28202776
DOI: 10.1126/scitranslmed.aam6064

Comment

Baring cellular souls

Alex K Shalek. Sci Transl Med. 2017.

. 2017 Feb 15;9(377):eaam6064.

doi: 10.1126/scitranslmed.aam6064.

Author

Alex K Shalek¹

Affiliation

¹ Institute for Medical Engineering & Science (IMES) and Department of Chemistry, MIT, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Email: shalek@mit.edu.

PMID: 28202776
DOI: 10.1126/scitranslmed.aam6064

Abstract

Coupling chemical approaches for disrupting DNA-protein complexes in intact nuclei with combinatorial barcoding enables high-throughput single-cell DNA sequencing.

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Sequencing thousands of single-cell genomes with combinatorial indexing.
Vitak SA, Torkenczy KA, Rosenkrantz JL, Fields AJ, Christiansen L, Wong MH, Carbone L, Steemers FJ, Adey A. Vitak SA, et al. Nat Methods. 2017 Mar;14(3):302-308. doi: 10.1038/nmeth.4154. Epub 2017 Jan 30. Nat Methods. 2017. PMID: 28135258 Free PMC article.

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Baring cellular souls

Affiliation

Baring cellular souls

Author

Affiliation

Abstract

Comment on

Publication types

MeSH terms

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Full Text Sources

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