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. 1987 Aug;68(4):585-93.

The histology of the eye after zosteriform spread of herpes simplex virus in the mouse

C Claoue  1 , T Hodges, T Hill, W Blyth, D Easty
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The histology of the eye after zosteriform spread of herpes simplex virus in the mouse

C Claoue et al. Br J Exp Pathol. 1987 Aug.

Abstract

A murine model of zosteriform spread of herpes simplex virus to the eye is reported. Viral antigens were demonstrated by a peroxidase-antiperoxidase technique in the trigeminal ganglion, iris, ciliary body, and cornea. The histology suggested a spontaneous bacterial superinfection during the later stages of the herpetic disease of the cornea. The relevance to human disease is discussed.

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