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. 2017 Mar 1;77(5):1051-1059.
doi: 10.1158/0008-5472.CAN-16-1336. Epub 2017 Feb 16.

The Tumor Microenvironment at a Turning Point Knowledge Gained Over the Last Decade, and Challenges and Opportunities Ahead: A White Paper from the NCI TME Network

Yves A DeClerck  1   2 , Kenneth J Pienta  3   4   5 , Elisa C Woodhouse  6 , Dinah S Singer  7 , Suresh Mohla  6
Affiliations

The Tumor Microenvironment at a Turning Point Knowledge Gained Over the Last Decade, and Challenges and Opportunities Ahead: A White Paper from the NCI TME Network

Yves A DeClerck et al. Cancer Res. .

Abstract

Over the past 10 years, the Tumor Microenvironment Network (TMEN), supported by the NCI (Bethesda, MD), has promoted collaborative research with the explicit goal of fostering multi-institutional and transdisciplinary groups that are capable of addressing complex issues involving the tumor microenvironment. The main goal of the TMEN was to generate novel information about the dynamic complexity of tumor-host interactions in different organ systems with emphasis on using human tissues and supplemented by experimental models. As this initiative comes to a close, members of the TMEN took time to examine what has been accomplished by the Network and importantly to identify the challenges and opportunities ahead. This consensus document summarizes for the broader scientific community discussions that occurred at the two final meetings of the TMEN in 2015 and 2016. Cancer Res; 77(5); 1051-9. ©2017 AACR.

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Conflict of interest statement

Disclosure of Potential Conflicts of Interest

S. Mohla is a consultant/advisory board member. No potential conflicts of interest were disclosed by the other authors.

Figures

Figure 1
Figure 1
TME Network 2006–2016. Areas of priority for the TMEN in the first 2006 RFA are indicated in blue; areas of priority for the 2011 RFA are indicated in red.
See this image and copyright information in PMC

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