Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2017 Feb 17;120(4):604-606.
doi: 10.1161/CIRCRESAHA.117.310440.

Calcific Aortic Valve Disease: A Battle of the Sexes

Affiliations
Editorial

Calcific Aortic Valve Disease: A Battle of the Sexes

Ana M Porras et al. Circ Res. .
No abstract available

Keywords: Editorials; aortic valve; aortic valve stenosis; calcification; comorbidity; fibrosis.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Possible routes for sex-specific divergence of CAVD
Halting the progression of CAVD will require knowledge of whether the disease exhibits sex bias from its onset, or if the initial disease process is shared across sexes, with subsequent differentiation.

Comment on

References

    1. Rajamannan NM, Evans FJ, Aikawa E, Grande-Allen KJ, Demer LL, Heistad DD, et al. Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. Circulation. 2011;124(16):1783–1791. - PMC - PubMed
    1. Owens DS, Katz R, Takasu J, Kronmal R, Budoff MJ, O'Brien KD. Incidence and progression of aortic valve calcium in the Multi-ethnic Study of Atherosclerosis (MESA) Am J Cardiol. 2010;105(5):701–708. - PMC - PubMed
    1. Wizemann T. Sex-Specific Reporting of Scientific Research: A Workshop Summary. Washington, D.C.: Institute of Medicine of the National Academies, Board on Population Health and Public Health Practice; 2012.
    1. Dobson LE, Fairbairn TA, Musa TA, Uddin A, Mundie CA, Swoboda PP, et al. Sex-related differences in left ventricular remodeling in severe aortic stenosis and reverse remodeling after aortic valve replacement: A cardiovascular magnetic resonance study. Am Heart J. 2016;175:101–111. - PubMed
    1. Carroll JD, Carroll EP, Feldman T, Ward DM, Lang RM, McGaughey D, et al. Sex-associated differences in left ventricular function in aortic stenosis of the elderly. Circulation. 1992;86(4):1099–1107. - PubMed