Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 May;47(5):1391-1402.
doi: 10.1007/s10803-017-3058-8.

Medical Conditions and Demographic, Service and Clinical Factors Associated with Atypical Antipsychotic Medication Use Among Children with An Autism Spectrum Disorder

Johanna K Lake  1   2 , Danica Denton  3 , Yona Lunsky  4   5 , Amy M Shui  6 , Jeremy Veenstra-VanderWeele  7   8 , Evdokia Anagnostou  9   10
Affiliations

Medical Conditions and Demographic, Service and Clinical Factors Associated with Atypical Antipsychotic Medication Use Among Children with An Autism Spectrum Disorder

Johanna K Lake et al. J Autism Dev Disord. 2017 May.

Abstract

This study aimed to describe rates of antipsychotic medication use and the association between their use and demographics, clinical variables, and the use of behavioral/education services among children with ASD. For children with ASD ages 2-11 (n = 4749) and those 12-17 (n = 401), 5.4 and 17.7% were prescribed at least one atypical antipsychotic medication respectively. In the multivariable model of young children, older age, use of multiple psychotropic medications, prior ASD diagnosis, non-white Hispanic race/ethnicity, and oppositional defiant problems were associated with antipsychotic use. Among older children, only older age was associated with antipsychotic use. In at least one age group, antipsychotic medication use was also related to behaviour, family and occupational therapy, public insurance, site region, externalizing problems, body mass index, and sleep and gastrointestinal problems.

Keywords: Atypical antipsychotic medication; Autism spectrum disorder; Children.

PubMed Disclaimer

References

    1. J Am Acad Child Adolesc Psychiatry. 2014 Feb;53(2):237-57 - PubMed
    1. Pediatr Clin North Am. 2012 Feb;59(1):175-87, xii - PubMed
    1. Sleep. 2000 Dec 15;23(8):1043-51 - PubMed
    1. Eur Neuropsychopharmacol. 2009 Sep;19(9):629-35 - PubMed
    1. J Child Adolesc Psychopharmacol. 2011 Dec;21(6):571-9 - PubMed

MeSH terms

LinkOut - more resources