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. 2017 Feb 16;65(4):582-584.
doi: 10.1016/j.molcel.2017.02.002.

Expanding the CRISPR Toolbox: Targeting RNA with Cas13b

Rodolphe Barrangou  1 , Charles A Gersbach  2
Affiliations
Free article

Expanding the CRISPR Toolbox: Targeting RNA with Cas13b

Rodolphe Barrangou et al. Mol Cell. .
Free article

Abstract

In this issue of Molecular Cell, Smargon et al. (2017) unearth Cas13b from type VI-B CRISPR-Cas immune systems and characterize its RNA-guided, RNA-targeting activity, including regulation by the novel co-factors Csx27 and Csx28, as well as non-specific collateral RNA damage.

Keywords: CRISPR; Cas; Cas13b; genome editing.

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