Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jan-Mar;9(1):13-17.
doi: 10.4103/0974-7796.198899.

A prospective randomized comparative trial between open subinguinal and loupe assisted subinguinal varicocelectome: A single center experience

Hari Gopal Vyas  1 , Vimal Bhandari  1 , Anup Kumar  2 , Biswajit Nanda  2 , Harbinder Singh  2 , Subroto Bhowmick  1
Affiliations

A prospective randomized comparative trial between open subinguinal and loupe assisted subinguinal varicocelectome: A single center experience

Hari Gopal Vyas et al. Urol Ann. 2017 Jan-Mar.

Abstract

Introduction: In our study, we reviewed efficacy and complication rates of open subinguinal varicocelectomy (OSV) and loupe assisted subinguinal varicocelectomy (LASV) using seminal and hormonal parameters in a prospective randomized study.

Materials and methods: We prospectively studied 60 males with Grade 2 and Grade 3 varicocele. Thirty patients underwent OSV and the other 30 patients underwent LASV. Intra-operative and post-operative complications along with pre-operative and post-operative seminal, hormonal parameters and testicular volume were compared between the groups.

Results: Sperm count, motility and morphology increased significantly in both groups, but the improvement was significantly better in LASV group. (Group A - improvement in sperm count, motility and morphology by 25%, 8.5%, 10.3%, respectively and in Group B - improvement in sperm count, motility and morphology by 110%, 68.59%, 71.1%, respectively. Decrease in serum follicular stimulating hormone (FSH), luteinizing hormone (LH) and increase in serum testosterone were significant in both groups, but the improvement was significantly better in LASV group. (Group A - serum FSH and LH decreased by 17.2%, 23%, respectively and serum testosterone increased by 13.7% and in Group B - serum FSH and LH decreased by 56.9%, 56.65%, respectively and serum testosterone increased by 95.9%). The recurrence (OSV = 13.2% and LASV = 0, P = 0.01) and complication rates were significantly lower in LASV group.

Conclusion: Our study shows that LASV is significantly better than OSV regarding efficacy and complication rates.

Keywords: Loupe assisted subinguinal varicocelectomy; open subinguinal varicocelectomy; varicocele.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None.

Figures

Figure 1
Figure 1
Allocation of patients in the study
See this image and copyright information in PMC

References

    1. Steeno O, Knops J, Declerck L, Adimoelja A, van de Voorde H. Prevention of fertility disorders by detection and treatment of varicocele at school and college age. Andrologia. 1976;8:47–53. - PubMed
    1. Kass EJ, Belman AB. Reversal of testicular growth failure by varicocele ligation. J Urol. 1987;137:475–6. - PubMed
    1. Paduch DA, Niedzielski J. Repair versus observation in adolescent varicocele: A prospective study. J Urol. 1997;158:1128–32. - PubMed
    1. Gorelick JI, Goldstein M. Loss of fertility in men with varicocele. Fertil Steril. 1993;59:613–6. - PubMed
    1. Zampieri N, Zuin V, Corroppolo M, Ottolenghi A, Camoglio FS. Relationship between varicocele grade, vein reflux and testicular growth arrest. Pediatr Surg Int. 2008;24:727–30. - PubMed