Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Nov 30:10:240-245.
doi: 10.2174/1874192401610010240. eCollection 2016.

Does Body Mass Index Affect Mortality in Coronary Surgery?

Affiliations

Does Body Mass Index Affect Mortality in Coronary Surgery?

Aristotle D Protopapas. Open Cardiovasc Med J. .

Abstract

Introduction: The Body Mass Index (BMI) quantifies nutritional status and classifies humans as underweight, of normal weight, overweight, mildly obese, moderately obese or morbidly obese. Obesity is the excessive accumulation of fat, defined as BMI higher than 30 kg/m2. Obesity is widely accepted to complicate anaesthesia and surgery, being a risk factor for mediastinitis after coronary artery bypass grafting (CABG). We sought the evidence on operative mortality of CABG between standard BMI groups.

Materials and methodology: A simple literature review of papers presenting the mortality of CABG by BMI group: Underweight (BMI ≤ 18.49 kg/m2), normal weight (BMI 18.5-24.9 kg/m2), overweight (BMI 25.0-29.9 kg/m2), mild obesity (BMI 30.0-34.9 kg/m2), moderate obesity (BMI 35.0-39.9 kg/m2), or morbid obesity (BMI ≥ 40.0 kg/m2).

Results: We identified 18 relevant studies with 1,027,711 patients in total. Their variability in size of samples and choice of BMI groups precluded us from attempting inferential statistics. The overall cumulative mortality was 2.7%. Underweight patients had by far the highest mortality (6.6%). Overweight patients had the lowest group mortality (2.1%). The group mortality for morbidly obese patients was 3.44%.

Discussion: Patients with extreme BMI's undergoing CABG (underweight ones more than morbidly obese) suffer increased crude mortality. This simple observation indicates that under nutrition and morbid obesity need be further explored as risk factors for coronary surgery.

Keywords: Body Mass Index; Coronary Artery Bypass; Evidence based medicine; Mortality; Obesity; Risk stratification.

PubMed Disclaimer

Figures

Fig. (1)
Fig. (1)
A simple graph of mortality from CABG in decreasing order of BMI.

References

    1. Report of a WHO consultation. [No authors listed] Obesity: preventing and managing the global epidemic. World Health Organ Tech Rep Ser. 2000;894: i-xii:1–253. - PubMed
    1. Wilson P.W., Grundy S.M. The metabolic syndrome: practical guide to origins and treatment: Part I. Circulation. 2003;108(12):1422–1424. doi: 10.1161/01.CIR.0000089505.34741.E5. - DOI - PubMed
    1. Hollenbeak C.S., Murphy D.M., Koenig S., Woodward R.S., Dunagan W.C., Fraser V.J. The clinical and economic impact of deep chest surgical site infections following coronary artery bypass graft surgery. Chest. 2000;118(2):397–402. doi: 10.1378/chest.118.2.397. - DOI - PubMed
    1. Prasad U.S., Walker W.S., Sang C.T., Campanella C., Cameron E.W. Influence of obesity on the early and long term results of surgery for coronary artery disease. Eur. J. Cardiothorac. Surg. 1991;5(2):67–72. doi: 10.1016/1010-7940(91)90003-3. - DOI - PubMed
    1. Tolpin D.A., Collard C.D., Lee V.V., Elayda M.A., Pan W. Obesity is associated with increased morbidity after coronary artery bypass graft surgery in patients with renal insufficiency. J. Thorac. Cardiovasc. Surg. 2009;138(4):873–879. doi: 10.1016/j.jtcvs.2009.02.019. - DOI - PubMed