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Comment
. 2017 Jan 21:4:4.
doi: 10.21037/sci.2016.12.02. eCollection 2017.

There will be blood: hematopoiesis control by mediator subunit MED12

Thomas G Boyer  1
Affiliations
Comment

There will be blood: hematopoiesis control by mediator subunit MED12

Thomas G Boyer. Stem Cell Investig. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Comment on

  • MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.
    Aranda-Orgilles B, Saldaña-Meyer R, Wang E, Trompouki E, Fassl A, Lau S, Mullenders J, Rocha PP, Raviram R, Guillamot M, Sánchez-Díaz M, Wang K, Kayembe C, Zhang N, Amoasii L, Choudhuri A, Skok JA, Schober M, Reinberg D, Sicinski P, Schrewe H, Tsirigos A, Zon LI, Aifantis I. Aranda-Orgilles B, et al. Cell Stem Cell. 2016 Dec 1;19(6):784-799. doi: 10.1016/j.stem.2016.08.004. Epub 2016 Aug 25. Cell Stem Cell. 2016. PMID: 27570068 Free PMC article.

References

    1. Clark AD, Oldenbroek M, Boyer TG. Mediator kinase module and human tumorigenesis. Crit Rev Biochem Mol Biol 2015;50:393-426. - PMC - PubMed
    1. Keightley MC, Layton JE, Hayman JW, et al. Mediator subunit 12 is required for neutrophil development in zebrafish. PLoS One 2011;6:e23845. 10.1371/journal.pone.0023845 - DOI - PMC - PubMed
    1. Kämpjärvi K, Järvinen TM, Heikkinen T, et al. Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia. Oncotarget 2015;6:1884-8. 10.18632/oncotarget.2753 - DOI - PMC - PubMed
    1. Aranda-Orgilles B, Saldaña-Meyer R, Wang E, et al. MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell 2016;19:784-799. 10.1016/j.stem.2016.08.004 - DOI - PMC - PubMed
    1. Kim NH, Livi CB, Yew PR, et al. Mediator subunit Med12 contributes to the maintenance of neural stem cell identity. BMC Dev Biol 2016;16:17. 10.1186/s12861-016-0114-0 - DOI - PMC - PubMed

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