Acute kidney injury in pancreatic surgery; association with urine output and intraoperative fluid administration

Abstract

Background: Acute kidney injury (AKI) is a devastating postoperative complication. Intraoperative urine output is assumed to reflect patient's intravascular volume and kidney function. We thus evaluated the incidence of postoperative AKI and its association with intraoperative urine output and the volume of fluid administered.

Methods: A retrospective study on 153 consecutive patients admitted to Tel Aviv Medical Center for pancreatic surgery.

Results: The incidence of AKI in patients undergoing pancreatic surgery was 9.8%. Oliguria was not a predictor of AKI. There was no association between the amount of fluids administered and AKI. Pulmonary disease is an independent predictor of AKI. AKI is an independent predictor of mortality.

Conclusions: AKI is common in patients undergoing pancreas surgeries and is associated with high mortality. Neither urine output, nor the volume of fluids administered correlate with postoperative AKI. Low diuresis is therefore not a sole marker for fluid administration.

Keywords: Acute kidney injury; Pancreatic surgery; Perioperative management; Urine output.