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Case Reports
. 2017 May;37(3):293-295.
doi: 10.3343/alm.2017.37.3.293.

A Puzzling "Switch" in Blood Type Following Blood Transfusion

Affiliations
Case Reports

A Puzzling "Switch" in Blood Type Following Blood Transfusion

Luiza Akria et al. Ann Lab Med. 2017 May.
No abstract available

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Conflict of interest statement

Authors' Disclosures of Potential Conflicts of Interest: No potential conflicts of interests relevant to this article were reported.

Figures

Fig. 1
Fig. 1. Forward and reverse ABO/D typing of the patient using a gel technique with the DiaMed IH-1000 Automated Blood Screening System (Bio-Rad). Blood group was determined as: (A) A+ upon arrival, (B) A+ at 12 hr from admission, and (C) O+ at day 7 (post admission). The anti-A column is magnified in all gel cards to emphasize the change from double population (DP) to lack of agglutination.
Fig. 2
Fig. 2. ABO genotyping based on sequence-specific primer (SSP) PCR using RBC Ready Gene ABO kit (Inno-Train DiagnostiK GmbH, Kronberg, Germany). Internal control PCR products are indicated by arrows. (A) Blood from patient upon admission; genotyping consistent with blood type A. (B) Blood from patient 12 hr after arrival; genotyping consistent with blood type A. (C) Blood from patient 7 days post admission; genotyping consistent with blood type O. (D) Patient skin biopsy; genotyping consistent with blood type O. Note: blood type A is distinguished from blood type O based solely on the “non O1” position (*) band.

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