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Editorial
. 2017 Mar;25(3):351-353.
doi: 10.1016/j.joca.2017.01.016.

Time to be positive about negative data?

T Vincent  1 , A-M Malfait  2
Affiliations
Editorial

Time to be positive about negative data?

T Vincent et al. Osteoarthritis Cartilage. 2017 Mar.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict statement

Dr. Vincent is on the Editorial Board of OAC, and Dr. Malfait serves as an Associate Editor.

Figures

Figure 1
Figure 1
Number of publications by year using mice in OA research. Data was generated by searching the terms ((((mouse) OR murine) OR mice)) AND osteoarthritis in Pubmed, (von Loga and Vincent, “Animal models in Osteoarthritis”, in “Rheumatology” 7th Edition, in review).
See this image and copyright information in PMC

References

    1. Smith MM, Clarke EC, Little CB. Considerations for the design and execution of protocols for animal research and treatment to improve reproducibility and standardization: "DEPART well-prepared and ARRIVE safely". Osteoarthritis and cartilage. 2016 - PubMed
    1. Ranstam J, Cook JA. Considerations for the design, analysis and presentation of in vivo studies. Osteoarthritis and cartilage. 2016 - PubMed
    1. Glasson SS, Askew R, Sheppard B, Carito BA, Blanchet T, Ma HL, Flannery CR, Kanki K, Wang E, Peluso D, et al. Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis and rheumatism. 2004;50(8):2547–2558. - PubMed
    1. Majumdar MK, Askew R, Schelling S, Stedman N, Blanchet T, Hopkins B, Morris EA, Glasson SS. Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis. Arthritis and rheumatism. 2007;56(11):3670–3674. - PubMed
    1. Little CB, Mittaz L, Belluoccio D, Rogerson FM, Campbell IK, Meeker CT, Bateman JF, Pritchard MA, Fosang AJ. ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo. Arthritis and rheumatism. 2005;52(5):1461–1472. - PubMed

Publication types