The Dark Age(ing) of the Inflammasome
- PMID: 28228276
- DOI: 10.1016/j.immuni.2017.02.009
The Dark Age(ing) of the Inflammasome
Abstract
Mechanisms that contribute to healthy aging remain obscure. In a recent issue of Nature Medicine, Furman et al. (2017) describe that dietary caffeine inhibits the NLRC4 inflammasome, which is associated with disease-free aging.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.Nat Med. 2017 Feb;23(2):174-184. doi: 10.1038/nm.4267. Epub 2017 Jan 16. Nat Med. 2017. PMID: 28092664 Free PMC article.
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