Synaptonemal complex and crossing-over: structural support or interference?
- PMID: 282284
- DOI: 10.1038/hdy.1978.92
Synaptonemal complex and crossing-over: structural support or interference?
Abstract
Positive cross-over interference is attributed to the prevention of crossing-over by the growing synaptonemal complex. This conjecture is based on a report in the literature that the selection of prospective cross-over sites may actually precede a proper synapsis of homologous chromosomes during meiotic prophase. A genetic test of this notion is suggested using a properly marked trisomic configuration, applicable to a variety of organisms.
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