Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Feb;10(2):e003480.
doi: 10.1161/CIRCOUTCOMES.116.003480. Epub 2017 Feb 22.

Young Women With Acute Myocardial Infarction: Current Perspectives

Affiliations
Review

Young Women With Acute Myocardial Infarction: Current Perspectives

Rachel P Dreyer et al. Circ Cardiovasc Qual Outcomes. 2017 Feb.

Abstract

In recent years, there has been growing public awareness and increasing attention to young women with acute myocardial infarction (AMI), who represent an extreme phenotype. Young women presenting with AMI may develop coronary disease by different mechanisms and often have worse recoveries, with higher risk for morbidity and mortality compared with similarly aged men. The purpose of this cardiovascular perspective piece is to review recent studies of AMI in young women. More specifically, we emphasize differences in the epidemiology, diagnosis, and management of AMI in young women (when compared with men) across the continuum of care, including their pre-AMI, in-hospital, and post-AMI periods, and highlight gaps in knowledge and outcomes that can inform the next generation of research.

Keywords: coronary artery disease; myocardial infarction; phenotype; prevalence.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Potential Mediators of Post AMI Outcomes among Young Women with AMI. Abbreviations: AMI=acute myocardial infarction.
Figure 2
Figure 2
Young Women with AMI – Action Items and Future Directions.

References

    1. Lichtman JH, Lorenze NP, D’Onofrio G, Spertus JA, Lindau ST, Morgan TM, Herrin J, Bueno H, Mattera JA, Ridker PM, Krumholz HM. Variation in recovery: Role of gender on outcomes of young ami patients (virgo) study design. Circ Cardiovasc Qual Outcomes. 2010;3:684–693. - PMC - PubMed
    1. Pilote L, Karp I. Genesis-praxy (gender and sex determinants of cardiovascular disease: From bench to beyond-premature acute coronary syndrome) Am Heart J. 2012;163:741–746. e742. - PubMed
    1. American Heart Association. The Go Red for Women Campaign. Available at: http://www.goredforwomen.org. Accessed December 10, 2016.
    1. Mehta LS, Beckie TM, DeVon HA, Grines CL, Krumholz HM, Johnson MN, Lindley KJ, Vaccarino V, Wang TY, Watson KE, Wenger NK, American Heart Association Cardiovascular Disease in Women, Special Populations Committee of the Council on Clinical Cardiology CoE, Prevention CoC, Stroke N, Council on Quality of C, Outcomes R Acute myocardial infarction in women: A scientific statement from the american heart association. Circulation. 2016;133:916–947. - PubMed
    1. Beckie T. Biopsychosocial determinants of health and quality of life among young women with coronary heart disease. Current Cardiovascular Risk Reports. 2014;8:1–10.

Publication types