Tumour evolution: Epigenetic and genetic heterogeneity in metastasis

Comment

Gemma K Alderton. Nat Rev Cancer. 2017.

. 2017 Feb 23;17(3):141.

doi: 10.1038/nrc.2017.11.

No abstract available

Comment on

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer.
Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Allen B, Kundu D, Chatterjee K, Wong F, Jiao Y, Kohutek ZA, Hong J, Attiyeh M, Javier B, Wood LD, Hruban RH, Nowak MA, Papadopoulos N, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA. Makohon-Moore AP, et al. Nat Genet. 2017 Mar;49(3):358-366. doi: 10.1038/ng.3764. Epub 2017 Jan 16. Nat Genet. 2017. PMID: 28092682 Free PMC article.
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
McDonald OG, Li X, Saunders T, Tryggvadottir R, Mentch SJ, Warmoes MO, Word AE, Carrer A, Salz TH, Natsume S, Stauffer KM, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JW, Iacobuzio-Donahue CA, Feinberg AP. McDonald OG, et al. Nat Genet. 2017 Mar;49(3):367-376. doi: 10.1038/ng.3753. Epub 2017 Jan 16. Nat Genet. 2017. PMID: 28092686 Free PMC article.