Protein Networks in Alzheimer's Disease

Affiliations

¹ Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.
² The Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Ole Worms Allé 3, 8000 Aarhus C, Denmark. Electronic address: runerasmussen@dandrite.au.dk.

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Comment

Eva Meier Carlsen et al. Cell Syst. 2017.

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. 2017 Feb 22;4(2):153-155.

doi: 10.1016/j.cels.2017.02.006.

¹ Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.
² The Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic EMBL Partnership for Molecular Medicine, Department of Biomedicine, Aarhus University, Ole Worms Allé 3, 8000 Aarhus C, Denmark. Electronic address: runerasmussen@dandrite.au.dk.

Abstract

Overlap of RNA and protein networks reveals glia cells as key players for the development of symptomatic Alzheimer's disease in humans.

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.
Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, Lah JJ, Levey AI. Seyfried NT, et al. Cell Syst. 2017 Jan 25;4(1):60-72.e4. doi: 10.1016/j.cels.2016.11.006. Epub 2016 Dec 15. Cell Syst. 2017. PMID: 27989508 Free PMC article.