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Case Reports
. 2017 Jun;42(6):458-460.
doi: 10.1097/RLU.0000000000001608.

FDG PET to Diagnose Neurolymphomatosis in a Case of Triple-Hit B-Cell Lymphoma

Caroline Bund  1 , Céline Heimburger, Philippe Trensz, Cécile Fohrer, Stéphane Kremer, Izzie-Jacques Namer
Affiliations
Case Reports

FDG PET to Diagnose Neurolymphomatosis in a Case of Triple-Hit B-Cell Lymphoma

Caroline Bund et al. Clin Nucl Med. 2017 Jun.

Abstract

A 46-year-old man with stage IV triple-hit B-cell lymphoma diagnosed in February 2016 was treated with chemotherapy. He was followed classically with FDG PET/CT, which assessed the complete metabolic response in June 2016. In July 2016, he had autologous stem cell transplantation. Two months later, he underwent an FDG PET/CT for revaluation. It showed intense FDG uptake in the medullary canal from cervical 4 to thoracic 4, bilateral cervical 7 to thoracic 8, and right thoracic 9 to 12 nerve roots, leading to the diagnosis of neurolymphomatosis. A clinical cervical radiculopathy and spinal MRI results reinforced this diagnosis.

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