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. 1986;3(2):123-6.
doi: 10.3109/07420528609066356.

No circadian rhythms of serotoninergic, alpha-, beta-adrenergic and imipramine binding sites in rat brain regions

A Di Lauro  1 , C P Giannini, G Muscettola, A M Greco, P de Franciscis
Affiliations

No circadian rhythms of serotoninergic, alpha-, beta-adrenergic and imipramine binding sites in rat brain regions

A Di Lauro et al. Chronobiol Int. 1986.

Abstract

Bmax values of the specific binding of [3H]-WB 4101, [3H]-dihydroalprenolol, [3H]-spiperone and [3H]-imipramine to various rat brain regions were determined at 4 hr intervals over 24 hr under circadian conditions. No significant circadian rhythm of binding sites number was found for any receptor investigated in cerebral cortex, hypothalamus or brain stem. Some methodological issues are discussed.

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