Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Feb 16:12:639-650.
doi: 10.2147/COPD.S123994. eCollection 2017.

Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD

Affiliations
Review

Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD

Daniel R Ouellette et al. Int J Chron Obstruct Pulmon Dis. .

Abstract

COPD is highly prevalent and associated with substantial morbidity and mortality. Clinicians have long been aware that patients with COPD have problems with cognition and are susceptible to mood (depression) and anxiety disorders. With the increasing awareness of COPD as a multisystem disorder, many studies have evaluated the prevalence of neuropsychiatric conditions in patients with COPD. This review presents evidence regarding the prevalence of neuropsychiatric conditions (cognitive disorders/impairment, depression/anxiety) in COPD, their risk factors, and their impact on relevant outcomes. It also discusses both assessment and treatment of neuropsychiatric conditions and makes recommendations for improved screening and treatment. The findings suggest that clinicians caring for patients with COPD must become familiar with diagnosing these comorbid conditions and that future treatment has the potential to impact these patients and thereby improve COPD outcomes.

Keywords: COPD; anxiety disorders; cognitive impairment; hypoxemia; mood disorders; pulmonary rehabilitation.

PubMed Disclaimer

Conflict of interest statement

Disclosure Salary support was provided by Investigator Awards from the Canadian Institutes of Health Research (CIHR) and the Fonds de la Recherche du Québec - Santé (FRQS) (Lavoie). The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
Contributing factors to cognitive deficits in patients with COPD.a Note: aCause–effect relationships between the contributing factors, cognitive defects, and COPD are not implied.

References

    1. Mannino DM, Homa DM, Akinbami LJ, Ford ES, Redd SC. Chronic obstructive pulmonary disease surveillance: United States, 1971–2000. MMWR Surveill Summ. 2002;51:1–16. - PubMed
    1. Pauwels RA, Rabe KF. Burden and clinical features of chronic obstructive pulmonary disease (COPD) Lancet. 2004;364(9434):613–620. - PubMed
    1. National Heart Lung, and Blood Institute . Data fact sheet. Chronic obstructive pulmonary disease; [Accessed June 6, 2016]. Available from: http://www.apsfa.org/docs/copd_fact.pdf.
    1. Public Health Agency of Canada . Chronic Pulmonary Obstructive Disease (COPD) Ottawa: Public Health Agency of Canada; [Accessed March 24, 2016]. Available from: http://www.phac-aspc.Gc.ca/cd-mc/publications/copd-mpoc/ff-rr-2011-eng.php.
    1. Cdc.gov. Centers for Disease Control and Prevention. National Center for Health Statistics Data brief 63: Chronic obstructive pulmonary disease among adults aged 18 and over in the United States, 1998–2009. [Accessed March 4, 2016]. Available from: http://www.cdc.gov/nchs/data/databriefs/db63_tables.pdf#2.

MeSH terms