Differentiation of atypical Parkinson syndromes

Günter U Höglinger^{1

2}, Jan Kassubek³, Ilona Csoti⁴, Reinhard Ehret⁵, Heinz Herbst⁶, Ingmar Wellach⁷, Jürgen Winkler⁸, Wolfgang H Jost⁹

Affiliations

¹ Department of Neurology, Technische Universität München, Munich, Germany. guenter.hoeglinger@dzne.de.
² Department of Translational Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen Str. 17, 81677, Munich, Germany. guenter.hoeglinger@dzne.de.
³ Department of Neurology, University of Ulm, Ulm, Germany.
⁴ Gertrudis-Kliniken, Biskirchen, Germany.
⁵ Office for Neurology, Berlin-Steglitz, Germany.
⁶ Office for Neurology, Stuttgart, Germany.
⁷ Office for Neurology/Ev. Amalie Sieveking-Krankenhaus, Hamburg, Germany.
⁸ Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
⁹ Parkinson Hospital Ortenau/University of Freiburg, Wolfach, Germany.

PMID: 28243754
DOI: 10.1007/s00702-017-1700-4

Review

Differentiation of atypical Parkinson syndromes

Günter U Höglinger et al. J Neural Transm (Vienna). 2017 Aug.

. 2017 Aug;124(8):997-1004.

doi: 10.1007/s00702-017-1700-4. Epub 2017 Feb 27.

Authors

Günter U Höglinger^{1

2}, Jan Kassubek³, Ilona Csoti⁴, Reinhard Ehret⁵, Heinz Herbst⁶, Ingmar Wellach⁷, Jürgen Winkler⁸, Wolfgang H Jost⁹

Affiliations

¹ Department of Neurology, Technische Universität München, Munich, Germany. guenter.hoeglinger@dzne.de.
² Department of Translational Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Feodor-Lynen Str. 17, 81677, Munich, Germany. guenter.hoeglinger@dzne.de.
³ Department of Neurology, University of Ulm, Ulm, Germany.
⁴ Gertrudis-Kliniken, Biskirchen, Germany.
⁵ Office for Neurology, Berlin-Steglitz, Germany.
⁶ Office for Neurology, Stuttgart, Germany.
⁷ Office for Neurology/Ev. Amalie Sieveking-Krankenhaus, Hamburg, Germany.
⁸ Department of Molecular Neurology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
⁹ Parkinson Hospital Ortenau/University of Freiburg, Wolfach, Germany.

PMID: 28243754
DOI: 10.1007/s00702-017-1700-4

Abstract

In distinction to idiopathic Parkinson's disease (PD), the diagnosis of atypical Parkinson syndromes comprises dementia with Lewy bodies (DLB), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). We set out to write a state-of-the-art guideline as to which investigations and examinations help to differentiate PD vs. atypical Parkinson syndromes in clinical routine.

Keywords: Corticobasal degeneration; Dementia with Lewy bodies; Multiple system atrophy; Parkinson’s disease; Progressive supranuclear palsy.

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Differentiation of atypical Parkinson syndromes

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Differentiation of atypical Parkinson syndromes

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